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Major Projects (Alzheimer’s research UK)

Alzheimer’s Research UK

The Major project grant scheme can also be used to fund “added value” sub-studies of existing or planned clinical trials that are not being funded as part of a core trial. Examples include testing biomarkers, imaging or digital outcome measures in a subgroup of participants to help validate new measures for use in dementia.

Duration: Up to five years.

Provided to cover salaries (research, technical, students etc), equipment, animal costs and running costs (consumables, travel etc).

Application form

Applications are made via our grant application website.

Grant schemes only appear on this website when the round is open and we are accepting new applications.

Review process

Alzheimer’s Research UK is a member of the Association of Medical Research Charities and follows their guidelines for best practice in peer review. Grants are awarded entirely on scientific merit in relation to ARUK’s remit and on the basis of open competition. The quality of the application and applicants is the key determinant of outcome, although the strength of the dementia research environment within the institution is also considered.

Triage

Three expert panel members from our Grant Review Board (GRB), who are not conflicted carries out an in-depth assessment of the applications drawing on their specific areas of expertise, and score each application A triage of the applications is carried out by a sub-set of GRB members to determine which applications move forward in the review process. Scoring and Review criteria are available here.

Rebuttal Opportunity

Before final review, applicants are given the opportunity to respond to the feedback from the GRB members. This rebuttal stage allows applicants to address any concerns or questions raised by the reviewers, providing clarifications or additional information to support their application.

Lived Experience Review

Those applications which have human volunteers are sent for Lived Experience Review. As part of the application, applicants are required to write a Plain English proposal, which are sent to volunteers from the Lived Experience Involvement Group for comments, and for scoring. The comments are made available to the GRB members and incorporated into discussion at the board meeting.

GRB Meeting and In-Depth Discussion

Following the rebuttal, the GRB holds an in-depth discussion of each application, incorporating both the original proposal and the rebuttal comments. This process includes input from experts on the panel and individuals with lived experience of dementia. The aim is to ensure a comprehensive review before funding decisions are made.

Final Funding Approval

Based on the in-depth discussions and assessments, the GRB makes recommendations for funding.

Specialties

Neurosciences

Eligibility Requirements

The lead applicant and point of contact must be based in a UK academic/research institution. However, the application can include industry partners as well as researchers or institutions outside the UK.

The Lead Applicant is expected to have a contract (fixed term or tenure) which covers the proposed duration of the grant. Alzheimer's Research UK can contribute to salaries of co-applicants that do not have tenure or fixed term contracts but not to Lead Applicant salaries.

If the Lead Applicant does not hold a tenure appointment, the application must include a co-applicant that does.

If the project requires ethical approval and/or Home Office licences, the award is dependent upon the requisite approvals being granted.

If you are applying for funds for translational research, such as drug discovery and development work, please consider a partnership with the Drug Discovery Alliance.

Sponsor Details

Sponsor Institute/Organizations: Alzheimer’s Research UK

Sponsor Type:

Address: 3 Riverside, Granta Park, Cambridge CB21 6AD

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