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C-OPN Data Challenge

Brain Canada Foundation

The main goal of the Canadian Open Parkinson Network (C-OPN) is to facilitate and accelerate Parkinson’s research. Brain Canada and Parkinson Canada have co-funded and partnered with C-OPN since 2018. To date, C-OPN has recruited over 2,300 participants and created a large nationwide database that includes de-identified participant data concerning demographics, symptoms, treatment approaches, standardized clinical assessments, neuroimaging data, genotyping for Parkinson’s gene variants, and a biobank of samples for further analysis of DNA, PBMCs and blood serum/plasma from study participants. These resources are open and accessible to researchers, clinicians and trainees in Canada and around the world, to help them answer their research questions in a faster and broader manner than would be possible if they were working solely out of their host institution or clinic.

FUNDS AVAILABLE

A total of $200,000 CAD is available in the competition to be awarded to the top 4 funding proposals. Successful grants are eligible for funding up to $50,000 each for a one-year term.

Final budgets of the successful projects will be based on the proposed work in the application, and the proposed budget and budget justification documents. The grant funds may be used to cover the costs incurred within Canada of research staff, materials and consumables, services or software costs, equipment (max. of $10,000), and publication costs for open science journals.

Grant funds may not be used for institutional overhead costs, or travel to meetings/conferences. To standardize budget submissions for all applicants, budget templates (Excel file) will be provided on the Parkinson Canada application website (SMApply). All applicants will be required to use the provided template to complete their proposed budget; applications that do not use this template may be disqualified.

AI Based Application Success Predictor

🎯 1. Program-Call Alignment & Scale

Platform Support Grants (PSG) fund shared resources (equipment, data platforms) at national/regional levels—typically large-scale, collaborative infrastructure proposals.

Future Leaders in Canadian Brain Research: For early-career investigators (within ~5 years of appointment), awarding $100K over 2 years for hypothesis-driven, transformative neuroscience 

Brain Cancer Translational Research Grants: Multidisciplinary teams (basic + clinical + lived-experience) aiming to develop diagnostics or treatments for brain cancer, with up to $1M over 3 years 

Mental Health & Innovation-Implementation: Fund projects with potential for national impact in pediatric neurodevelopmental health

2. High Scientific Merit & Creativity

All programs expect strong scientific rationale, clear innovation, and hypothesis-driven designs. Future Leaders encourages bold, unconventional ideas .

Platform and consortium programs demand demonstration of need and strategic capacity enhancement across research communities.

3. Team Composition & Stakeholder Engagement

Platform calls require community-wide collaboration to build shared infrastructure.

Cancer and pediatric network grants mandate inclusion of clinicians, basic scientists, and people with lived experience, ensuring patient-informed design .

Mental health and implementation programs require user engagement, implementation specialists, and multi-sector partnerships 

4. Feasibility & Demonstrated Capacity

Show evidence of feasibility (e.g., pilot data, preliminary results).

Demonstrate ability to execute and manage complex projects with milestones, infrastructure, and personnel plans.

5. Equity, Diversity & National Impact

Brain Canada emphasizes EDI, encouraging diverse applicant pools and inclusive research environments 

Programs like platform support and mental health focus on scalable national benefit, measurable outcomes, and sustainability.

6. Matching Funds & Leverage

For several calls (especially PSG and KBHN Innovation), applicants must secure matched funding (cash or in-kind)

Demonstrating multiple funding sources strengthens proposals.

7. Budget Realism & No Overheads

Budgets should align with typical Brain Canada structures (e.g., zero or low indirect costs).

Clearly justify expenditures, focusing on costs essential for execution.

8. Competitive & Multi-Stage Review

Most grants use registration/pre-proposal + full application phases.

Peer-review process with external scientific and sectoral experts (e.g., platforms, cancer).

Some calls involve interviews or advisory group selection.

📋 Summary Table

Predictor	How to Deliver It
Program fit	Target specific Brain Canada stream (Platform, Future Leaders, Cancer, Mental Health)
Scientific quality	Bold, hypothesis-driven ideas backed by data and novelty
Team & stakeholder makeup	Include clinicians, caretakers, community-users, EDI plans
Feasibility	Show preliminary work, timeline, capacity
EDI & impact orientation	Describe diverse team and national-scale outcomes
Funding leverage	Secure matched funds (cash/in-kind) where required
Budget alignment	Align with program norms, justify key costs
Review strategy	Pass registration, use peer review feedback, be ready for interviews

🛠 Pro Tips to Enhance Your Application

Engage Lived-Experience advisors early and integrate their input.

Plan matched funding early with institutional support letters.

Map your work to Brain Canada goals: capacity building, translation, national sustainability.

Highlight EDI in your team, methods, and research culture.

Budget sparingly, focusing on direct impact and excluding overheads.

Prepare for stage-gated call process; refine based on feedback.

Contact Brain Canada staff to clarify alignment and eligibility ahead of deadline.

Specialties

Neurosciences

Eligibility Requirements

Applications will be accepted from researchers, scholars, and health professionals conducting Parkinson’s research in Canada. The applicant must be a researcher who has completed formal training in health-related research. Applicants must have a research appointment and employment relationship with an approved institution. This research appointment must:

• allow the applicant to hold grant funding, pursue the proposed research project, to supervise trainees and to publish the results of their research.

• require the applicant to conform to institutional regulations concerning the conduct of research, the supervision of trainees and the employment conditions of trainees and/or support staff paid from the grant.

Applicants must be affiliated with and conduct research at an eligible: Canadian postsecondary institution or their affiliated institutions (including hospitals and research institutes). Applications are encouraged to be team-based and include two or more independent investigators from different institutions, or distinct research groups within the same institution.

Applicants and co-applicants that hold a research appointment, as described above, are prohibited from receiving the payment of a salary, stipend, honorarium, or any similar form of compensation from any Parkinson Canada or Brain Canada grant. Post-doctoral fellows or trainees are not eligible to apply for funding under this Program.

Eligible Countries:

Canada

Sponsor Details

Sponsor Institute/Organizations: Brain Canada Foundation

Sponsor Type: Corporate/Non-Profit

Address: 1200 McGill College Ave, Montreal, Quebec H3B 4G7, Canada

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