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Channelopathies and Translational physiology

University of Milano-Bicocca

University of Milano Bicocca

Main Areas of Interest

Channelopathies and translational physiology

Workplace: Channelopathies and Translational physiology lab, School of Medicine, University of Milano-Bicocca, Monza, Milano, Italy; Electrophysiology Unit, IMTC, San Donato Milanese, Italy

The main research areas of our group are:

Cardiac channelopathies: in vitro characterization of the functional consequences of genetic mutation related to cardiac arrhythmias.
Neuronal channelopathies: in vitro characterization of the functional consequences of genetic mutation related to several forms of epilepsy.
Muscle channelopathies: in vitro characterization of the functional consequences of genetic mutation related to myotonia.
Personalized medicine strategies in human channelopathies

Techniques You Will Learn

Experimental platforms/techniques you will learn during your program here:

Platforms for in vitro studies

Cell cultures (primary or stable cell lines)
Differentiation of cardiomyocytes from human iPSCs
Cellular electrophysiology (patch—clamp, automated patch-clamp, MEA system)
Intracellular calcium dynamics
Sarcomeres contractility measurements

In vitro assays

Cell culture establishment and maintenance
Cell transfection, Electroporation
Cell viability/toxicity assays
Immunofluorescence
Immunoblotting

Curriculum

6-8 weeks curriculum

The trainee will be provided with the opportunity of learning the basis of preclinical research in the field of channelopathies, having experiences of facing with clinical staff (cardiologist, neurologists) and basic researchers in an interdisciplinary and translational research environment
The trainee will be provided with the unique opportunity of experiencing the laboratory practice and to operate trainings on cellular electrophysiology and cellular biology
The trainee may also have the opportunity of collaborating on research projects, depending on the ongoing activities at the time of the Trainee’s visit
The trainee will be provided with the opportunity of participating to meetings, journal clubs, seminars,including those of the PhD in DIMET, of the Virgilio Program and UNIMIB seminars besides the seminars at the IMTC in San Donato
The trainee will have the opportunity to join collaborative research programs with national and international laboratories and companies ongoing at the Labs at the time of the Trainee’s visit
Please visit the websites below for more information:
http://www.dimet.org/contacts/
https://virgilioprogram.unimib.it/

Accommodation

Residence Luna

website (Italian; possible online reservation): https://www.residencelunadimonza.it/
website (English; possible online reservation): https://www.onlinereservations.com/?hotelid=1473933&gclid=CjwKCAjw4qCKBhAVEiwAkTYsPIcTkPVKr1mNoe377rtedHOawqpOe1HUI1YK6Sc_Y2FWbry-Mq8ESxoCGUkQAvD_BwE

Helios Hotel

website (Italian; possible online reservation): https://heliosmonza.com/it/
website (English; possible online reservation): https://heliosmonza.com/en/

Residenze Universitarie Bicocca

website (Italian; possible online reservation): https://bicocca.residenzesodexo.it/
website (English; possible online reservation): https://en.unimib.it/services/bicoccacampus/accommodation

Campus in-domus

website (Italian; possible online reservation): https://www.indomus.it/
website (English; possible online reservation): https://www.indomus.it/en/

Fees and Program Logistics

This program has the following durations available:

Duration	Fee
2 weeks	$875.00
6 weeks	$1,500.00
12 weeks	$2,750.00

This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.

Who Can Apply

All are eligible

Host Details

Host Name: Prof. Ilaria Rivolta

Affiliation: University of Milano-Bicocca

Address: Piazza dell'Ateneo Nuovo; 1, 20126 Milano MI; Italy

Website URL: https://en.unimib.it/

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.

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