Trialect

Active

Neurodegenerative Disorders

Gachon University, South Korea

Main Areas of Interest

The main research areas of our group are:

Basic mechanisms of neurodegenerative diseases
Genetics in neurodegenerative diseases
Molecular basis of diagnosis of misfolded proteins in neurodegenerative diseases
Biomarkers in neurodegenerative diseases
Screening of therapeutics against misfolded proteins in neurodegenerative diseases (e.g. small lmolecules with anti-aggregation properties towards protein amyloids of Alzheimer’s disease. Parkinson’s disease, Amyotrophic Lateral Sclerosis, etc.

Techniques You Will Learn

####Experimental techniques you will learn during your program here: fellows need to choose one neurodegenerative disease

generations of protein amyloids in in neurodegenerative diseases. (lectures & experiments)
TEM for characterizing amyloid fibrils (lectures & experiments)
Detection methods of protein amyloids in neurodegenerative diseases (lectures)
immunological assays (atypical ELISA: Multimer Detection System) of biomarkers (experiments)
Screening of small molecular therapeutics against misfolded proteins in neurodegenerative diseases.
2D and 3D cell culture using Crispr-Cas9 generated HEP293 cells with pathogenic variants from patients with Alzheimer’s disease. (lectures & experiments)
flow cytometry for characterization of cells (lectures & experiments)
cell viability/toxicity assays (necrosis, apoptosis, ROS, lipotoxicity, autophagy, senescence: lectures &experiments)
cell metabolism assays (enzymatic activity by spectrofluorimetric and chemiluminescencse-based assays: lectures & experiments)
immunoblotting & co-immunoprecipitation of biomarkers (as needed: lectures & experiments))
fluorescence and confocal microscope (lectures & experiments)

Curriculum

6-12 weeks curriculum

Fellows will be supported to settle down into their new environment (find appropriate accommodation,
locate amenities, etc.) and register at the research center at Gachon University, during which an
entrance card of the Gachon Bionano Research Institute will be issued. A desk space will be allocated.
Full induction (safety, laboratory practices, personal welfare, etc.) will be provided by registering to the
Korean Research Organization and going through online education program. I will arrange an initial
meeting with the fellow to discuss the objectives of the training and the expected mechanisms of their
fulfilment. Experimental plans with realistic timelines will then be decided.

The fellow will be fully trained to run each experiment. They will then be allowed to attempt the
experiment themselves, with the trainer present during their first run. They will be able to engage with
me (supervisor) and other members of the laboratory to discuss any aspects of the general running of
the laboratory or specific protocols that they require clarifications on. They will also be trained in how to
analyse and interpret their data. I will arrange a weekly or bi-weekly meeting with the fellow to discuss
and reflect on their progress and decide the next set of experiments based on data generated. A fellow
must keep adequate and accurate records of their work using the laboratory book provided.

The fellow will be given opportunity to partake in research group meetings and other academic activities
within the School and the University, including attending relevant bespoke workshops on research and
seminars. They will also be encouraged to present their work orally at a research group meeting at least
once before they complete their visit.

Towards the end of the training I will have a meeting with the fellow to discuss plans to publish their
work (if enough data collected) or disseminate their findings in a future conference. They will also be
assisted to identify existing or future opportunities, globally or within their original work environment,
that the training has empowered them to be eligible and competitive for and how they can be assisted
to access them and also integrate the knowledge and skills gained into their further research or
professional practice roles.

All throughout the training any peculiar challenges or specific requests of a fellow will be fully
considered to ensure a responsive, relevant and adequate training plan is developed for them.

Accommodation

Guest house/accommodation near the lab

Militopia Hotel (good quality):

Website (possible online reservation): http://www.militopiahotel.com/

Hotel Park Habio (good quality & close to the subway station):

Website (possible online reservation): http://www.hotelparkhabio.co.kr/en/m/

Yaja Hotel (good quality & close to the subway station):

Website (possible online reservation): https://www.agoda.com/yaja-hotel-wirye/hotel/seongnam-si-kr.html?cid=1844104

Gachon University dormitory (for international students)

need to check for availability as requested.

Fees and Program Logistics

This program has the following durations available:

Duration	Fee
2 weeks	$875.00
6 weeks	$1,500.00
12 weeks	$2,750.00

This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.

Who Can Apply

The fellow will be fully trained to run each experiment.

Host Details

Host Name: Dr. Seong Soo An

Affiliation: Gachon University, South Korea

Address: 1342 Seongnam-daero; Sujeong-gu; Seongnam-si; Gyeonggi-do; South Korea

Website URL: https://www.gachon.ac.kr/kor/index.do

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.

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Onsite/On-Campus Program

Fellowship - Basic/Translational/Clinical Research Program

Korea, Republic of

Application Review Deadline:

Jan 1st, 2024

Apply Now

Program Logistics and Administrative Fees

This program has the following durations available:

Duration	Fee
2 weeks	$875.00
6 weeks	$1,500.00
12 weeks	$2,750.00

Questions and Answers

Commonly asked questions about this program from the host and other attendees.

I am awardee under 'Priority' for a workshop on 'Neurodegenerative Disorders' to be organised in Korea. I am keen to participate for the workshop but need financial support or may be considered under merit category. Please help out and do the needful. Thanks. Rohit Goyal

You can visit our grant portal at https://trialect.com/program-grants-list

How should I apply for this program? Are there any procedures?

The upcoming programs get activated once in 3 months. Please register with us here https://trialect.com/program-list and push the notification button to get notified about the active program.