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Senior Research Awards

Crohn's & Colitis Foundation of America

Objective: To provide established researchers with funds to generate sufficient preliminary data to become competitive for funds from other sources such as the National Institutes of Health (NIH).

Senior Research Awards Costs: Total maximum award per year: $130,000 (subject to annual progress report approval).

Direct Costs: up to $118,182 per year
Indirect Costs: 10% of direct costs, or up to $11,818
Duration of Award: One to Three Years

AI Based Application Success Predictor

1. Alignment with Foundation Priorities

Clinical relevance & translational impact: CCF emphasizes studies addressing pragmatic clinical questions that can be implemented in practice and appear in high-impact journals or guidelines .

Focus on IBD challenges: Projects aligned with the “Challenges in IBD Research” priorities (e.g., personalized medicine, microbiome, health disparities) receive top priority .

👩‍🔬 2. Investigator Career Stage & Track Record

Career Development Awards: Best suited for early-career researchers (≤10 years post-degree) with relevant IBD experience, committed to building independent careers .

Senior Research Awards: Target established investigators with proven track records and preliminary data; fund pilots to support larger NIH-style proposals .

🧪 3. Quality of Study Design & Feasibility

Well-defined hypotheses, appropriate sample sizes, clear timelines, and realistic milestones are essential .

For clinical awards, demonstrated potential to generate influential publications or guide clinical practice is crucial .

🤝 4. Strong Mentorship & Institutional Support

Career Development and Fellowship awards require a committed mentor and evidence of protected research time (e.g., ≥80%) .

Senior awards and clinical investigator grants should include institutional backing, core facilities access, and interdepartmental or multicenter collaboration .

🧬 5. Innovation & Translational Potential

Projects that pioneer personalized approaches—like biomarker-driven treatment selection or new delivery systems—especially when moving toward practice change, perform well .

Innovative product development (e.g., IBD Ventures Smart Pills) reflects CCF’s interest in real-world solutions .

📈 6. Evidence of Future Funding Pathways

Senior Research Award proposals should lay out how generated data will form the basis for larger NIH or foundation funding .

Expectation: funded work leads to high-impact publications, clinical guideline citations, and "follow-on" grants

🔄 7. Structured Peer Review

All grants undergo rigorous peer review by IBD experts; quality of science, relevance, innovation, and feasibility are evaluated .

📋 Summary Table

Grant Type	Key Predictors of Success
Career Development / Fellowship	Early-stage, strong mentorship, protected time (≥80%), IBD focus
Senior Research Award	Proven track record, preliminary data, translational potential, scalability
Clinical Investigator-Initiated	Clinical relevance, practice impact, alignment with priority areas
IBD Ventures / Litwin Pioneers	Innovative product development or new clinical tools

✅ Tips to Strengthen Your CCF Application

Frame your project within the “Challenges in IBD Research” framework to show mission alignment.

Build a strong mentorship team, especially for junior awards, specifying roles and time commitment.

Develop clear milestones, sample size rationale, and time-structured aims.

Highlight translational impact—how it will change practice, lead to guidelines, or inform policy.

Plan for the future—lay out the grant pathway to NIH or similar agencies.

Demonstrate innovation via product or data platform development when applicable.

Ensure institutional support, with confirmed resources and collaborations included.

Specialties

Gastroenterology

Eligibility Requirements

Applicant must hold an MD and/or PhD (or equivalent degree) and must be employed by an institution (public non-profit, private non-profit, or government) that is engaged in health care and/or health-related research. He/she must have attained independence from his/her mentor. Eligibility is not restricted by citizenship or geography.

Proposal Eligibility: Proposal must be relevant to Inflammatory Bowel Disease (IBD) or Crohn's disease and/or ulcerative colitis. Only one application is allowed per applicant per submission date. Simultaneous submission of a Senior Research Award and a Training Award is not permitted.

Sponsor Details

Sponsor Institute/Organizations: Crohn's & Colitis Foundation of America

Sponsor Type: Corporate/Non-Profit

Address: 733 THIRD AVENUE, SUITE 510, NEW YORK, NY 10017

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