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CRI Irvington Postdoctoral Fellowship

Cancer Research Institute, Inc.

The CRI Irvington Postdoctoral Fellowship Program supports qualified young scientists at leading universities and research centers around the world who wish to receive training in fundamental immunology or cancer immunology.

A panel of scientists drawn from our Scientific Advisory Council rigorously evaluates each candidate, the intended sponsor and training environment, and the nature and feasibility of the proposed project.

The Cancer Research Institute recognizes that getting to the next great breakthrough in cancer treatment will require continued investment in fundamental research and training. CRI, therefore, invites postdoctoral fellows working in both fundamental immunology and tumor immunology to apply for funding.

CRI seeks hypothesis-driven, mechanistic studies in both immunology and tumor immunology. The applicant and sponsor should make every effort to demonstrate the potential of the proposed studies to directly impact our understanding of the immune system’s role in cancer.

In response to recent disruptions in federal funding, CRI is committing an additional $2.5 million in funding to support 10 additional postdoctoral fellowships over the next year. This investment directly supports early-career scientists, ensuring that we continue fostering the next generation of IO researchers.

Financial Information

Fellowships are for three years. Beginning with the March 1, 2025, deadline (for new awards beginning July 1, 2025), newly awarded fellowships provide a stipend of $74,000 for the first year, $76,000 for the second year, and $78,000 for the third year. An allowance of $5,000 per year is allotted to the host institution for use at the sponsor’s discretion to help pay for the fellow’s research supplies, travel to scientific meetings, health insurance, and/or childcare. CRI provides additional support for fellows to attend CRI’s annual International Cancer Immunotherapy Conference (CICON), and to participate in CRI’s Bioinformatics Bootcamp.

Deductions for administrative overhead are not allowed from either the stipend or the institutional allowance. Payments are made monthly in U.S. currency to the host institution.

Deadlines

The application deadlines are March 1 and September 1 annually; when those dates fall on the weekend or holiday, applications are due the following workday. Applications are due by 11:59 p.m. Eastern Time on these dates. Applicants are notified of fellowship committee decisions within approximately 10-12 weeks of the application deadline.

Fellowships can be activated four months after the application deadline but no later than one year following the deadline. Awards activate on the first of the month.

AI Based Application Success Predictor

1. Strong Focus on Cancer Immunology & Immunotherapy

CRI only funds projects that involve immune-based approaches to cancer, including discovery, biomarkers, translational networks, or clinical trials integrating immunological mechanisms.

✅ Predictor: Your proposal is firmly immunology‑based, not general oncology .

2. Early-Career Fellowship Excellence (e.g., Irvington, Immuno-Informatics)

CRI’s fellowships cater to postdoctoral trainees:

Feature robust mentorship plans and structured career development.

Teach writing, review, networking, and community-building within CRI’s immunology-focused ecosystem .

3. Translational Relevance — CLIP & Clinical Innovator Programs

Programs like CLIP (Clinic & Laboratory Integration Program) and Clinical Innovator Grants support investigator-led translational studies in immuno-oncology:

Require faculty-line status (e.g., tenure-track assistant professor) by award activation .

Favor studies that integrate clinical trial design with mechanistic biomarker insights and predictive immunotherapy endpoints.

4. Technology Innovation — Technology Impact Awards

Up to $300K over two years to translate novel platforms or analytics into immunotherapy research tools:

Focus on bioinformatics tools, instruments, assays, or models that accelerate immunotherapy research.

Proposals should exhibit high technical sophistication, innovative thinking, and transform the field

5. Scientific Innovation & Promotional Language

Funders like CRI reward cutting-edge ideas:

Proposals showing truly novel immunological hypotheses or technologies have higher success.

The use of well-calibrated "promotional language" (e.g., highlighting transformative potential, urgency) correlates with stronger funding outcomes

6. Feasible Workplan with Milestones

Accepted applications include:

Clear aims with realistic timelines and deliverables.

Milestone-based plans including risk mitigation and follow-on strategy.

Especially for high-dollar grants (CLIP, Innovator, Technology), your execution clarity is critical .

7. Strong Mentorship & Institutional Support

Early-career awards require:

Documented support from established cancer immunology leaders.

Institutional backing, especially for research infrastructure or lab space.

Evidence of participation in CRI cohorts or conferences helps

8. Career Trajectory & Long-term Impact

CRI aims to support researchers who:

Represent emerging future leaders (e.g., Lloyd J. Old STAR Awardees).

Show clear plans for follow-on funding and mentorship roles.

Provide evidence of high productivity (e.g., CRI produces hundreds of publications annually)

📋 Summary Table

Grant Program	Career Stage	Key Strengths for Success
Irvington / Immuno-Informatics Fellowships	Postdoc	Strong immunology training, mentor support
CLIP Grants	Early faculty (tenure-track)	Lab-clinic integration, translational design
Clinical Innovator Grant	Clinician-scientist	Phase I/II trials + mechanistic studies
Technology Impact Award	Faculty with innovation	Transformative immuno-tech platforms
Lloyd J. Old STAR Award	Mid-career leaders	Field impact, innovation leadership

✅ Tips for Strong CRI Applications

Clearly show immune‑focused innovation driving cancer therapy advances.

Craft a well-articulated translational vision (esp. for CLIP / clinical grants).

Emphasize novel technologies or computational tools in the immunotherapy sphere.

Use strategic language to communicate potential impact and novelty.

Provide detailed milestones, risk mitigation, and feasibility statements.

Secure strong mentorship letters and institutional support.

Showcase how funding will help you build toward future leadership in cancer immunology.

Specialties

Cancer

Eligibility Requirements

Applicant Eligibility

Applicants for the CRI Irvington Postdoctoral Fellowship Program must be working in areas directly related to immunology or cancer immunology. An eligible project must fall into the broad field of immunology with relevance to solving the cancer problem.
Applicants must have a doctoral degree by the date of award activation and must conduct their proposed research under a sponsor who holds a formal appointment as an assistant professor or higher rank at the host institution.
Applicants with 5 or more years of relevant postdoctoral experience at the time of award activation are not eligible, with the exception of M.D. applicants, who should not include years of residency in this calculation.
Only in exceptional circumstances will applicants who have already spent 3 or more years in a sponsor’s laboratory by the start date of fellowship be considered for a fellowship award.
The fellowship can be performed in the United States or abroad but must take place at a non-profit institution. There are no citizenship restrictions.
Only one fellow per sponsor may apply per application round, and faculty sponsors may not have more than three CRI-supported fellows at any time.
Resubmissions: Applicants are permitted to resubmit their fellowship application at a subsequent deadline provided that the new application is improved to reflect progress. Changes to the application should be addressed within the subsequent application.

Sponsor Details

Sponsor Institute/Organizations: Cancer Research Institute, Inc.

Sponsor Type: Corporate/Non-Profit

Address: 29 Broadway, Floor 4  New York, NY 10006-3111

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