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Fellowship Grant - post-doctoral fellowship Awards

ChadTough Defeat DIPG Foundation

The ChadTough Defeat DIPG grants are intended to incentivize novel approaches and spark innovation to find a cure for the deadliest pediatric brain cancer, DIPG. It is no easy task. But we are confident that by working together with the passionate doctors and researchers focused on making progress on this disease, children with DIPG will finally be able to look forward to a bright future.

We are committed to building the most comprehensive grant program for funding DIPG research. To achieve this goal, we offer three types of grants: Fellowship Grants, New Investigator Grants, and Game Changer Grants.

Awarded to outstanding pre-doctoral and post-doctoral fellows under the guidance of a mentor to help develop the next generation of leaders in DIPG research. $300,000 over 3 years (maximum of $100,000 per year) for post-doctoral fellows; $200,000 over 3 years (maximum of $67,000 per year) for pre-doctoral fellows.

Application Due: September 8, 2025

Available: March 3, 2025

Awarded: November 2025

Start: January 1, 2026

AI Based Application Success Predictor

1. ✳️ Alignment with the DIPG/DMG Mission

Your project must focus exclusively on DIPG/DMG research, addressing disease mechanisms, diagnostic tools, therapeutic strategies, or clinical intervention.

The Foundation funds only childhood brain cancer research targeting these devastating tumors.

2. 🎓 Appropriate Program for Career Stage & Project Type

Fellowship Grants (pre‑doc/post‑doc):

3-year support: up to $100K/year (post-doc) or $67K/year (pre-doc), for early researchers under mentor supervision.

New Investigator Grants:

Up to $400K over 3 years (max $135K/year). Supports newly independent faculty starting DIPG research or established investigators with no prior DIPG/DMG experience.

Game Changer Grants:

Up to $600K over 3 years (max $200K/year). Intended for high-risk, innovative strategies with transformative potential.

3. 🧪 Innovation & Translational Potential

Projects must present novel hypotheses or technologies directly relevant to DIPG.

Clinical trial‐ready strategies, advanced delivery platforms (e.g., convection-enhanced delivery, nanomedicine), or mechanistic breakthroughs are highly valued. Recent Game Changer awardees include those developing targeted drug delivery across the blood-brain barrier.

4. 🔄 Feasibility, Track Record & Mentorship

Fellowship applicants need a strong mentor, institutional support, and commitment of ≥75 % research time.

New Investigators must demonstrate faculty-level independence (tenure-track position, institutional support, lab space).

Game Changer applicants should show leadership appetite and prior productivity.

5. 🧭 Competitive, Peer-Reviewed Process

Applications are rigorously evaluated by the ChadTough Scientific Advisory Council, composed of DIPG experts; final decisions are made by the Foundation’s board.

6. 📆 Typical Timeline

LOI Window: March 1 – June 1

Full Proposal Deadline: September 1

Successful applications begin funding the following January.

✅ Summary Table: Key Elements for a Strong Application

Success Predictor	Why It Matters
Focused on DIPG/DMG	Ensures relevance to Foundation’s mission
Appropriate grant track	Aligns career stage and project scope with program goals
High novelty & translation	Projects must be cutting-edge with real patient impact
Feasibility & institutional support	Demonstrates capacity for execution and follow-up
Innovation & mentorship	Shows future leadership potential in DIPG research
Compelling LOI & full proposal	Entry into rigorous, competitive review pipeline

📚 Why ChadTough Matters

Since its inception, the foundation has awarded over $36 million to more than 90 scientists across 44 institutions worldwide, supporting career pipelines and breakthrough research in DIPG, a rare and lethal pediatric cancer.

Specialties

Cancer

Eligibility Requirements

 Applicant need not be a U.S. citizen or based at a U.S. institution.

 Applicant must not have received more than one prior fellowship.

 Applicant must commit at least 75% of full-time effort to research.

 Applicant must identify a mentor who will provide supervision, facilities, and research support.

 For post-doctoral applicants: o Applicant must hold an M.D. and/or Ph.D. by the application deadline. o Applicant must be no more than 6 years post-completion of last degree. o Applicant must be employed by an academic institution, nonprofit research institution, or laboratory.

Sponsor Details

Sponsor Institute/Organizations: ChadTough Defeat DIPG Foundation

Sponsor Type: Corporate/Non-Profit

Address: P.O. Box 907, Saline, MI 48176 | (734) 707-8732

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