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Young Investigator Grant

Cannonball Kids' Cancer Foundation

Cannonball Kids’ cancer Foundation was founded in 2014 by Michael and Melissa Wiggins, parents of Cannon Wiggins, who was diagnosed with Stage IV high-risk neuroblastoma when he was just 20 months old. During Cannon’s treatment, they learned that very little time, effort and funding is devoted to finding cures for children’s cancer compared to adult cancers, and as a result, children are unnecessarily and unjustly lost. CKc aims to stop the tragic reality of children suffering and dying because of the lack of research in the world of children’s cancer treatments. CKc believes "Research is the Key" that will unlock a cure, and the foundation has now awarded more than $4.5 million in research grants, providing an option for over 922 children who were told they had "no more options". The majority of those studies are first-oftheir-kind and are dispersed throughout 35 U.S. states, D.C., Canada, Scotland and Switzerland.

Award Amount & Duration

$100,000 over 3 years

Program Specific Evaluation Criteria

• Evidence of Mentor’s commitment to the PI’s career development plan

• Translational potential

AI Based Application Success Predictor

1. 🎯 Mission-Driven Focus: Pediatric Cancer

CKc funds only research that directly improves outcomes for children with cancer, especially when it:

Targets underfunded, rare, or pediatric-specific cancer types

Aims to develop less toxic, more effective treatments

Enhances quality of life and survivorship

💡 Strong Predictor: Clear pediatric focus; innovation targeted at survival and long-term wellness.

2. 🧪 Program-Relevant Grant Track

CKc offers two core funding streams:

Young Investigator Grant: ~$100,000 over 3 years — supports early careers to generate early-phase data.

Clinical Trial Grant: ~$200,000 over 3 years — supports first-in-human or Phase I–II trials.

✅ Predictor: Matching your career stage and research stage to the appropriate grant.

3. 🚀 Innovation with Translational Potential

Studies should be first-in-child or early clinical trials.

Projects must offer novel therapeutic strategies or biomarkers.

Proposals should focus on therapies with fewer side effects and better accessibility for diverse pediatric populations.

4. ✔️ Proven Feasibility & Strong Preliminary Data

Applications need well-rationalized preliminary data or proof-of-concept (especially for trial grants) or a clear early-career trajectory to full trials.

A structured and realistic timeline, milestones, and risk mitigation plan strengthen the application.

5. 👥 Track Record & Mentorship for Early Investigators

CKc emphasizes supporting clinical-investigator training pipelines.

Your profile should show a commitment to moving toward independent, trial-driving roles.

Mentorship, institutional support, and diverse backgrounds are prioritized.

6. 🔄 Rigorous Review Process & Pipeline Approach

Funding uses a two-stage LOI → full application process, reviewed by the CKc Scientific Advisory Board.

Only 17 full applications selected from 44 LOIs in the 2024 cycle—only 4 grants awarded.

CKc aims for high uptake of clinical trials—they report 94% of trial grants are novel.

7. 🌍 Equity, Diversity, & Access Priority

CKc favors projects focused on underserved or marginalized pediatric populations.

Researchers from diverse backgrounds and early-stage investigators are encouraged.

📅 Application Timeline & Process

LOI window: March 1 – June 1

Full application by: September 1

Awards begin: January 1 following year

CKc uses invite-only application after LOI and review.

✅ Summary Table

Predictor	Why It Matters
Pediatric focus	Foundation exclusively funds childhood-cancer research
Appropriate grant stream	Align career stage with Young Investigator vs. Trial
Translatable and novel approach	CKc supports first-of-kind and quality-of-life-enhancing therapies
Preliminary data & feasibility	Feasibility ensures funding confidence
Early career development	CKc invests in investigator pipelines
Multi-stage selection rigor	LOI success leads to competitive full application
DEI & underserved emphasis	Align with CKc’s mission for equitable impact

🔭 Why CKc Matters

CKc has committed over $4.5 million across more than 40 research grants in 35 U.S. states and international centers, generating 922 new treatment options for children. Many CKc-supported projects have led to NIH funding, clinical trial expansion, and lasting impact.

Specialties

Cancer

Eligibility Requirements

• PI must hold an academic appointment at the instructor level or higher

• Research must be within 5 years of completing a training fellowship in Pediatric Hematology/Oncology or a closely related discipline that has direct clinical contact with pediatric cancer patients

• Research must be within 2-3 years to translation to a clinical trial or already associated with a clinical trial

Sponsor Details

Sponsor Institute/Organizations: Cannonball Kids' Cancer Foundation

Sponsor Type: Corporate/Non-Profit

Address: 1555 Howell Branch Rd., Suite C202 Winter Park, FL 32789 321-325-5392 info@cannonballkidscancer.org

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