Trialect

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Drug release modeling

Faculty at the University of Patras

The program offers an introduction to theoretical modeling of drug release kinetics

Main Areas of Interest

Controlled drug release
Pharmacokinetics
Formulation design

Specialties

Drug Delivery

Biomedical Engineering

Molecular Biology

Drug Development

Pharmacology

Medical Devices

Techniques You Will Learn

Numerical Monte Carlo simulations
Analytical techniques
Empirical models

Modules

Module 1: Introduction to Drug Release Kinetics

Overview: Explore the fundamentals of drug release kinetics and the importance of controlled drug release in pharmaceuticals.
Topics:
- Controlled drug release
- Types of release profiles (immediate, delayed, sustained)
- Overview of pharmacokinetics and formulation design
Techniques: Empirical models of release profiles

Module 2: Description of Drug Release Mechanisms

Overview: Understand various drug release mechanisms and their significance in drug delivery systems.
Topics:
- Basics of drug release mechanisms
- Factors determining the dominant mechanism
- Mathematical description of release
Techniques: Empirical models, analytical and numerical techniques

Module 3: Diffusion-Controlled Drug Delivery

Overview: Delve into diffusion as a key mechanism in drug delivery and its applications in controlled release systems.
Topics:
- Principles of diffusion in drug delivery
- Mathematical modeling of diffusion processes
- Case studies of diffusion-controlled systems
Techniques: Diffusion equation and numerical Monte Carlo simulations

Module 4: Chemical Reaction-Controlled Drug Delivery

Overview: Explore chemical reactions as a mechanism for controlling drug release and their role in pharmacokinetics.
Topics:
- Mechanisms of chemically controlled release
- Factors affecting reaction-controlled release profiles
- Applications in pharmacokinetics
Techniques: Empirical models and numerical Monte Carlo simulations

Module 5: Reaction-Diffusion Systems in Drug Delivery

Overview: Study the interplay of reaction and diffusion processes in complex drug delivery systems.
Topics:
- Release affected by both diffusion and chemical reactions
- Modeling reaction-diffusion systems
- Applications in formulation design
Techniques: Analytical and numerical methods for modeling

You can also bring your case studies for analysis, so teaching can be customized based on your interest

Program Fee


Total Number of Modules	5
Time duration of Each module	35 minutes
Total Program Cost	$510.42

This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.

Who Can Apply

Basic level knowledge of differential equations

Host Details

Host Name: George Kalosakas

Affiliation: Faculty at the University of Patras

Address: University Campus, Rio, GR-26504, Greece

Website URL: https://www.upatras.gr/en/

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.

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