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Notice of Special Interest (NOSI): Research to Address Ending the HIV Epidemic Initiative Goals Relevant to Substance Using Populations At-Risk for or Living with HIV

National Institutes of Health

The purpose of this NOSI is to support a broad spectrum of multi-disciplinary, substance use research to address the goals of the four pillars, including Diagnose, Treat, Prevent, and Respond of the ‘ Ending the HIV Epidemic in the U.S. (EHE) ’ initiative. Projects proposed in response to this NOSI are required to meet the needs of the substance using populations who are at high risk for contracting HIV or living with HIV in the geographically defined EHE priority areas within the U.S.

The National Institute on Drug Abuse (NIDA) has been working with other NIH Institutes, Centers, and Offices to facilitate EHE efforts as they apply to substance using populations. This NOSI is part of a targeted effort to expand the scope of the Institute’s portfolio in the EHE research area. Community engagement efforts in developing and implementing jurisdictional EHE plans, as well as in the planning, design, and delivery of local HIV prevention and care services, is vital to the initiative’s success. Consistent with the HHS stance on the ‘whole-of-society effort’, this NOSI seeks projects involving partners and end users from all sectors of society working together, including people with HIV or at risk for HIV; city, county, tribal, and state health departments and other agencies; local clinics and healthcare facilities; healthcare providers; providers of medication-assisted treatment for opioid use disorder; professional associations; advocates; community- and faith-based organizations; the justice system, and academic and research institutions, among others.

NIDA seeks to enhance HIV prevention and service delivery efforts specific to PWUD through major implementers, including the Centers for Disease Control and Prevention (CDC), Health Resources and Services Administration (HRSA), Indian Health Service (IHS), and Substance Abuse and Mental Health Services Administration (SAMHSA), and other providers of HIV and substance use prevention and care services. Collaboration with one or more of these implementing partners is strongly encouraged. Applicants should also consider innovative ways to enhance engagement and co-creation efforts across community, health departments, and implementing partners and community-based and outreach approaches that overcome barriers to conventional prevention and treatment access.

Applications responding to this NOSI must demonstrate clear plans to leverage key scientific advances in HIV prevention, diagnosis, treatment, and outbreak response. They must include EHE prioritized jurisdictions where HIV transmission occurs most frequently. If proposing research in localities outside the specified jurisdictions, a strong rationale (supported by epidemiological data) for selecting the site must be provided. NIDA strongly encourages applicants to address one of the research priorities of NIDA HIV Research Program ( HRP ).

This notice applies to due dates on or after February 5, 2023 and subsequent receipt dates through January 08, 2027.

NOT-DA-23-013

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Interdisciplinary

Medical - Basic Science

Medical - Translational

Medical

Medical - Clinical Science

Eligibility Requirements

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type:

Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA

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