The Division of Cancer Prevention (DCP) at the National Cancer Institute (NCI) announces this Notice of Special Interest to encourage current grant or cooperative agreement awardees to apply for administrative supplement funds to support the development of tools and strategies to increase the participation of individuals from all population subgroups who are representative of people for whom the parent grant intervention may be indicated. DCP led or co-led programs appropriate for this opportunity include Cancer Prevention and Control Clinical Trials Grant Program, Cancer Prevention Clinical Trials Network (CP-CTNet), NCI Community Oncology Research Program (NCORP) Research Bases, NCORP Community Sites and NCORP Minority/Underserved Community Sites, Prevention of HPV-related Cancers in HIV-infected individuals: United States-Latin American-Caribbean Clinical Trials Network: Partnership Centers Program and the NCI Cancer Screening Research Network: ACCrual, Enrollment, and Screening Sites (ACCESS) Hub. The proposed strategies and tools should be designed to promote inclusion of historically underserved populations in clinical trials - by identifying and reducing enrollment barriers at the organizational, participant, or protocol design level.
The NCI is providing this opportunity to support supplemental proposals to implement and evaluate promising clinical trial recruitment and retention tools and strategies for cancer screening, prevention and symptom management clinical trials, as well as quality-of-life studies embedded within treatment and imaging studies. The research solicited through this opportunity includes but is not limited to hypothesis-driven strategies that are directed toward NIH-designated U.S. health disparity populations , which include Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities as well as older adult populations. Proposals may include one or more strategies and may be applied to one or more studies or sites. Applications should include a prospective plan for evaluation of the performance of the proposal. Well-defined metrics for evaluating the effects/outcomes of the proposed strategy are also required.Some examples of potential outcomes include percentage of achievement of pre-specified goals for diverse contacts and accrued participants and meeting recruitment and retention milestones in the predicted accrual period as well as results of participant surveys, staff feedback surveys, focus group reports, comparison with past recruitment performance, pre- and post-test results of participant or staff education programs.
NOT-CA-23-071
Sponsor Institute/Organizations: National Institutes of Health
Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA
Jun 30, 2025
Varies
Affiliation: National Institutes of Health
Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA
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