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Clinician Scientist Development Grant (CSDG)

American Cancer Society

Grant Overview

The Clinician Scientist Development Grant (CSDG) supports full-time faculty members in becoming independent investigators as clinician scientists. This grant is designed for people trained primarily as clinicians who want to maintain clinical practice and conduct cancer research.

Grant Term and Budget

Awards may be for 3 to 5 years with $135,000 a year for direct costs, plus 8% allowable indirect costs.

Application Deadlines

June 1, 2025 and December 1, 2025

AI Based Application Success Predictor

1. Alignment with ACS Priority Areas 🎯

Your proposal must align with at least one of ACS's six priority research areas:
etiology, screening/diagnosis, treatment, survivorship, health equity, or obesity/HEAL 
Clearly articulate how your work advances one of these domains.

2. Investigator Stage & Track Record 🧠

For Research Scholar Grants, applicants must be full-time faculty within 10 years of their first independent appointment and not holding another R01-equivalent grant 

Analysis shows funded applicants often had ≥3 years of research experience, with 72% having prior publications vs. 37% for unfunded applicants 

MD–PhDs tend to succeed more often than PhDs than pure MDs, but a strong track record is critical .

3. Scientific Quality & Innovation

ACS aims to “fund the best science” — proposals are rigorously peer reviewed based on significance, innovation, and approach

Strong grantsmanship is essential: projects should address big, unanswered questions, be hypothesis-driven, and avoid “domino” aims that depend on prior results 

Use clear, concise, typo-free writing accessible to both specialist and general reviewers 

4. Structured, Feasible Aims & Design

Limit to 2–3 self-contained aims, each testable independently

Provide solid preliminary data, and include contingency plans — follow-up aims should not hinge on earlier successes .

5. Robust Peer & Community Review Process

Applications receive two assigned independent reviews, discussed in a Peer Review Committee (12–25 experts + community members), followed by review by the Discovery Scientific Council

Funded projects are typically ranked highly during these deliberations.

6. Institutional Commitment & Mentorship

Applicants must confirm institutional support, including space, resources, and oversight, and ensure eligibility (e.g., no competing major grants) .

7. Thoughtful Budget & Timeline

Grants vary by mechanism:

RSGs: up to $215K/year (plus 10% indirect), ≤4 years

Discovery Boost: $135K/year, 2 years

TheoryLab Collaborative: ~$60K for 1-year pilot, co-led by two investigators
Ensure budgets are well-justified, appropriately scoped, and matched to project milestones.

8. Communication & Grantsmanship

Use promotional but accurate language to highlight novelty, as such language is statistically linked to funding success .

Craft compelling Specific Aims and an engaging abstract to grab reviewers' attention early

9. Resubmission & Persistence

Applicants receive review critiques and can revise/resubmit; persistence and incorporation of feedback boost success

📝 Summary Table

Predictor	What to Address
ACS priority area	Clearly link to one of six research focus areas
Investigator eligibility	Faculty ≤10 years post-independence; no other R01s
Track record	≥3 years experience; strong publication history
Innovation & aims	Big ideas; 2–3 self-contained, hypothesis-driven aims
Preliminary data	Present and support feasibility
Budget & timeline	Well-justified and milestone-aligned
Institutional support	Space, resources, formal backing
Writing & grantsmanship	Clarity, readability, minimal jargon, engaging voice
Peer review readiness	High-scoring in committee and council evaluations
Resubmission planning	Use critique to strengthen future applications

🔧 Pro Tips

Engage early with ACS Scientific Directors to align your idea with suitable funding mechanisms.

Have a non-specialist read your Specific Aims to ensure clarity.

Balance novelty with feasibility — don’t overpromise.

Practice resubmissions; feedback-driven improvements increase competitiveness.

Specialties

Cancer

Eligibility Requirements

You ARE eligible to submit a proposal if you:

Work at a US academic institution or eligible non-profit
Have a doctoral degree, an active clinical license, and participate in clinical care
Are not a current or former principal investigator (PI) of an individual mentored training grant
Have NOT had an R-level or equivalent grant as PI

Sponsor Details

Sponsor Institute/Organizations: American Cancer Society

Sponsor Type: Corporate/Non-Profit

Address: 270 Peachtree St NW, Suite 1300 Atlanta , GA 30303

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