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AACR-Hope Scarves Metastatic Breast Cancer Innovation and Discovery Grant

American Association for Cancer Research (AACR)

Grant Amount$50,000 USD

Grant Term1 Year

Start of Grant TermNovember 1, 2025

Application DeadlineJuly 24, 2025 1:00 PM

Decision DateOctober 2025

Additional InformationAdditional details regarding this grant can be found in the Program Guidelines and Application Instructions. Final determinations of eligibility will not be completed until the AACR is in receipt of the submitted application.

Research Project Criteria

Research projects may be basic, clinical, or translational in nature and must have direct applicability and relevance to metastatic breast cancer. Applications are invited from researchers currently studying metastatic breast cancer, as well as investigators with experience in other areas of cancer or biomedical research.

AI Based Application Success Predictor

🎯 1. Alignment with Mission & Funding Track

AACR supports cancer research from basic discovery to early translational and team science. Specific programs include Innovative Research Grants, Independent Research Grants, and Team Science Awards

Choose the exact AACR opportunity that matches your career stage, cancer type, or research focus. Misalignment can derail eligibility or reviewer interest .

2. High Innovation & Scientific Rigor

AACR prioritizes high-risk, high-reward research 

Applications are evaluated for novelty, sound methodology, and realistic feasibility—balancing innovation with a credible plan .

3. Strong Investigator Profile

Applicants should clearly demonstrate:

Relevant publications and prior funding

Career trajectory, including early-impact markers

For mid-career Grants (e.g., Trailblazer), expect criteria like tenure and past R01-equivalent awards 

4. Feasibility with Milestones & Team Structure

Provide 2–3 clear, standalone aims, backed by preliminary data with contingency plans .

For team-based or collaborative grants, define distinct but complementary roles among PIs, with interdisciplinary strengths

5. Peer Review-Friendly Presentation

Clear, well-organized aims pages significantly influence reviewer engagement 

Throughout submission, tailor language to emphasize fit, avoid jargon, and reflect both scientific promise and alignment with AACR goals .

6. Diversity, Equity & Inclusion (DEI) Awareness

AACR funds applicants from diverse backgrounds, institutions, and countries, and has supported DEI innovation grants .

Highlighting your institutional context and inclusion efforts can strengthen your application.

7. Administrative Completeness & Compliance

Submit LOIs where required (e.g., Trailblazer: LOI due June, full in September) .

Use correct templates, include all bios, budgets, letters, and adhere strictly to formatting and submission instructions .

8. Persistence & Reapplication Strategy

AACR emphasizes the importance of learning from peer critiques and resubmitting improved proposals—seed grants often serve as precursors to larger awards .

Attend AACR workshops like “Meet the Reviewers” to refine applications .

📋 Summary Table

Predictor	Recommended Action
Program Alignment	Pick exact funding track, articulate fit
Innovation + Rigor	Present bold yet methodologically sound proposals
Investigator Strength	Emphasize publications, prior funding, tenure
Feasibility & Team Logic	Use clear aims, milestones, disciplinary roles
Reviewer-Friendly Framing	Structure aims page, use accessible language
DEI & Institutional Context	Highlight diversity and institutional fit
Complete Submission	Meet LOI deadlines; follow formatting rules
Feedback & Resubmission	Use critiques to refine and reapply

🛠 Pro Tips to Strengthen Your AACR Application

Craft a standout Aims page—use it to hook reviewers with clear, impactful objectives .

Align innovation with feasibility—demonstrate boldness but support it with data and timelines .

Engage in peer feedback and AACR events, like “Meet the Reviewers,” to align expectations .

Frame diversity and institutional context explicitly where relevant.

Plan for future federal scale grants—explain how your AACR effort builds toward NIH/P01 R01 ambitions .

Specialties

Cancer

Eligibility Requirements

All applicants with questions about eligibility should contact AACR’s Research and Grants Administration (RGA) at grants@aacr.org before submitting an application.

At the start of the grant term on November 1, 2025, applicants must:

Have a doctoral degree (PhD, MD, MD/PhD, or equivalent) in a related field and not currently be a candidate for a further doctoral degree.
Be an independent investigator working at an academic, medical, or non-profit research institution.
- If eligibility is based on a future position, the position must be confirmed at the time of application, and CANNOT be contingent upon receiving this grant.
- If the future position is at a different institution than the applicant’s current institution, the applicant must contact AACR’s RGA at grants@aacr.org before submitting their application for information on additional verification materials/signatures that may be required.
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship.
Employees or subcontractors of a U.S. government entity or for-profit private industry are not eligible. Employees or subcontractors of a U.S. government entity or for‐profit private industry may serve as Collaborators, but no grant funds may be directed toward these individuals.

Sponsor Details

Sponsor Institute/Organizations: American Association for Cancer Research (AACR)

Sponsor Type: Corporate/Non-Profit

Address: 615 Chestnut St., 17th Floor Philadelphia, PA 19106-4404 USA Telephone: 215-440-9300 Email: aacr@aacr.org

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