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Funding Opportunity




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ALSF 2025 ‘A’ Award Grant

Alex's Lemonade Stand Foundation (ALSF)

The purpose of the ‘A’ Award Grant is to advance ALSF’s mission to find cures and better treatments for childhood cancers by providing support to early career scientists who want to establish a career in pediatric oncology research. The ideal applicant has an original project that is not currently being funded. Demonstration of a future commitment to pediatric cancer investigation as well as institutional support for the career development of the investigator are critical components of a successful application. A mentor is required, and a career development plan must be included.

Application Timeline and Review 

• A full proposal must be submitted that meets all guideline criteria as well as all eligibility criteria; otherwise, applications will be administratively rejected. 

• Proposals will be reviewed by an independent panel of experts according to the NIH recognized peer-review process.

• Restrictions: 

o ALSF adheres to the NIH salary cap for principal investigator. 

o Indirect costs are not allowed. 

o The grant may not be renewed; one no-cost extension request is allowed with the Final Report 

o Other budget items may include the following: fringe benefits, travel, supplies, and equipment under $10,000. ALSF funds cannot be used for tuition remission. View ALSF’s complete budget policy. 

• If utilizing a subcontract or subaward, you must include this expense in the budget. 

o No indirect costs will be paid. 

o The PI’s institution is responsible for disbursing funds for subawards and/or subcontracts.

• Applicant institutions must be based in the United States or Canada. Applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations.

Applicants must have an MD, PhD or MD/PhD (DO, MBBS or equivalent) and be within five years of their first faculty appointment as an Assistant Professor at the time that their application is submitted as well as: 

o MD and MD/PhD must be within ten years of their terminal research degree or end of post-graduate clinical training (whichever date is later). 

o PhD must be within ten years of their terminal research degree. 

• More senior Assistant Professors, as well as Associate and Full Professors, are ineligible. If still at the Instructor level, the applicant must have a firm commitment from the Department Chair/Division Chief at the time of grant submission for an Assistant Professor position within one year of receiving the award. 

• A minimum of 75% of the applicant’s time during the ‘A’ Award period must be allocated as non-clinical protected time for all research activities. This percentage of time includes both ‘A’ Award activities and the applicant’s other research responsibilities. 

• Mentor(s) must be identified and must be in the applicant’s home institution. A comentor whose research expertise is aligned with the application could be added from an outside institution. 

• Applicants cannot be the Principal Investigator (PI) of a K99/R00 or other independent, nationally competitive award (e.g., R01 or equivalent, P or U award) that has been funded or recommended for funding (i.e., will be funded) any time before the ‘A’ Award grant start date.o Please review ALSF’s R01 equivalency policy on the grant recipients page of our website. If the applicant has an award not listed on the equivalency policy, contact ALSF at least 4 weeks before the application due date to determine eligibility. 

• Applicants may have mentored-career development grants (such as K01, K08, K23, K25) or mentored-research grants (such as ACS-Clinician Scientist Development Grant; DoD Physician Research Award) from other funding sources during the ‘A’ Award period, but there must be clear documentation of how scientific and budgetary overlap will be avoided. 

• Applicants currently holding an ALSF Young Investigator (YI) Grant may apply. If the ‘A’ Award is given, it would supersede the YI grant if there is an overlap in the funding periods.

Eligible Countries:

Sponsor Institute/Organizations: Alex's Lemonade Stand Foundation (ALSF)

Sponsor Type: Corporate/Non-Profit

Address: 3 Bala Plaza West Bala Cynwyd, PA 19004

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Grant

Letter Of Intent Deadline:

Jun 16, 2025

Final Deadline:

Jun 16, 2025

Funding Amount:

$800,000

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