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Personalized Healthcare Fellowship Program
Host: Dept. of Pathology & Clinical Bioinformatics Unit, ErasmusMC, The Netherlands
Main Areas of Interest
By Prof. Dr. Ing. Peter J. van der Spek:
As a geneticist and bioinformatician I study how variations in our genome contribute to the differences between health and disease. Moreover, we have learned from pharmacogenetics studies that various different genetic variants also can contribute to therapy response and drug metabolism. Sharing therapy response data is therefore essential to optimize and roll out these novel personalized healthcare strategies in day to day clinical practice. In order to implement Personalized Medicine we need to use the Whole genome sequence for diagnostics in order to decide which targeted treatment is most optimal for a given patient at a specific point in time of the disease process. Insight in molecular pathways that can be activated or repressed by biologicals (agonists or antibody based antagonists is the modern way to treat disease.
About Prof. Dr. Ing. Peter J. van der Spek:
Peter J. van der Spek has been appointed as professor and head of the department of bioinformatics at the Erasmus MC. He obtained his doctoral degree in 1995 in the field of molecular carcinogenesis by cloning cancer predisposition genes.
Van der Spek has 6 years of pharmaceutical experience from Akzo-Nobel and Johnson & Johnson and holds several international academic appointments in Japan, Australia, and the USA. The bioinformatics group at the Erasmus MC focuses on the support of datamining and analysis. This expertise is used for fundamental research, molecular diagnostics, molecular imaging, (forensic) molecular biology and support of clinical trials. Erasmus MC is one of the largest medical centers in the Netherlands.
Van der Spek runs an immunological research program which provides the biological and technological basis for the bioinformatics group. It concentrates on the way the immune system and the genome as a whole contribute to the evolution, development, structure, and function of vital organs in our body.
Specialties
Techniques You Will Learn
Techniques related to
- Genetics
- Bioinformatics
- Big Data
- Molecular Diagnosis
Learn about Galaxy Project: https://galaxyproject.org/use/erasmus-mc/
Curriculum
2-4 week Personalized Medicine traineeships at ErasmusMC
The Erasmus University Medical Center (Erasmus MC) based in Rotterdam, Netherlands, affiliated with Erasmus University and home to its faculty of medicine, is the "largest and one of the most authoritative scientific University Medical Centers in Europe." Furthermore, the hospital is the largest of the eight university medical centers in the Netherlands, both in terms of turnover and number of beds. The Erasmus MC ranks #1 of the top European institution in clinical medicine and #20 in the world according to the Times Higher Education rankings.
ErasmusMC offers 2-4 week personalized medicine internships illustrating the power of molecular diagnostics followed by targeted treatment strategies.
During the internship complex genetic cases will be discussed to illustrate the variable clinical presentation linked to specific perturbed molecular pathways underlying auto-immune and auto-inflammatory disorders.
The intracellular metabolism in monocytes, macrophages and dendritic cells (DCs) appears crucial for the function of these critical controllers of innate and adaptive immunity. They undergo profound metabolic reprogramming in response to environmental cues, such as hypoxia or nutrient alterations, but also upon triggering by danger signals and cytokines. Therefore, metabolic alterations in monocytes, macrophages and DCs appear crucial to maintain immune homeostasis and metabolic dysregulation could lead to disease pathology. You will be part of a multidisciplinary team comprising of internists, pathologists immunologists, molecular biologists and bioinformaticians studying patients suffering from auto-immune and or auto-inflammatory disorders.
Accommodation
Try airbnb.com in Rotterdam
Fees and Program Logistics
This program has the following durations available:
| Duration | Fee |
|---|---|
| 2 weeks | $875.00 |
| 4 weeks | $1,500.00 |
This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.
Who Can Apply
All physicians and biomedical scientists from around the world can apply
Host Details
Host Name: Prof. Dr. Ing. Peter J. van der Spek
Affiliation: ErasmusMC
Address: Doctor Molewaterplein 40, 3015 GD Rotterdam, Netherlands
Website URL: https://www.erasmusmc.nl/
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.
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Onsite/On-Campus Program
Fellowship - Basic/Translational/Clinical Research Program
Netherlands
Application Review Deadline:
Dec 1st, 2024
Program Logistics and Administrative Fees
This program has the following durations available:
| Duration | Fee |
|---|---|
| 2 weeks | $875.00 |
| 4 weeks | $1,500.00 |
This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.
Who Can Apply
All physicians and biomedical scientists from around the world can apply
Host Details
Host Name: Prof. Dr. Ing. Peter J. van der Spek
Affiliation: ErasmusMC
Address: Doctor Molewaterplein 40, 3015 GD Rotterdam, Netherlands
Website URL: https://www.erasmusmc.nl/
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.
Questions and Answers
Commonly asked questions about this program from the host and other attendees.
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