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Personalized Healthcare
(5/5) - 1 reviews
Host: Dept. of Pathology & Clinical Bioinformatics Unit, ErasmusMC, The Netherlands
Main Areas of Interest
Areas of Interest
Bioinformatics
- Data mining and analysis.
- Integration and analysis of mutations and multi-omics data.
- Genotype-phenotype correlations in health and disease.
Molecular Genetics
- Molecular carcinogenesis.
- Cloning of predisposition cancer genes.
- Genetic variations and their impact on biological pathways.
Big Data Applications in Medicine
- Application of innovative technologies in medical care.
- Molecular diagnostics.
- Clinical trials and their data requirements.
Circadian Biology
- Genetic influence on circadian rhythms.
- Biological pathway analyses.
Pharmacogenetics
- Genetic factors affecting drug metabolism.
- Personalized medicine based on genetic profiles.
Molecular Diagnostics:
- Advanced techniques for diagnosing complex genetic conditions.
- Understanding the link between genetic mutations and clinical presentations.
- Case studies of genetic disorders with variable clinical outcomes.
Auto-Immune and Auto-Inflammatory Disorders:
- Mechanisms underlying auto-immune and auto-inflammatory diseases.
- Clinical presentations and molecular pathways involved.
- Role of intracellular metabolism in immune cells.
Metabolic Reprogramming in Immune Cells:
- Metabolic changes in monocytes, macrophages, and dendritic cells.
- Impact of environmental cues (e.g., hypoxia, nutrient alterations) on immune cell function.
- Consequences of metabolic dysregulation in disease pathology.
Specialties
Techniques You Will Learn
Bioinformatics Techniques
- Data mining and machine learning applications in genetics.
- Use of bioinformatics tools for multi-omics data analysis.
- Genomic data visualization and interpretation.
Molecular Biology Techniques
- DNA/RNA extraction and sequencing.
- Gene cloning and expression analysis.
Clinical Trial Data Management
- Design and management of clinical trial databases.
- Statistical analysis of clinical trial data.
- Data integrity and compliance with regulatory standards.
Circadian Rhythm Analysis
- Techniques for monitoring and analyzing circadian rhythms.
- Use of bioluminescence and other markers to study circadian genes.
Pharmacogenomics
- Techniques for assessing drug response based on genetic profiles.
- High-throughput screening methods.
- Personalized medicine strategies.
Learn about Galaxy Project: https://galaxyproject.org/use/erasmus-mc/
Curriculum
2-4 week Personalized Medicine traineeships at ErasmusMC
The Erasmus University Medical Center (Erasmus MC) based in Rotterdam, Netherlands, affiliated with Erasmus University and home to its faculty of medicine, is the "largest and one of the most authoritative scientific University Medical Centers in Europe." Furthermore, the hospital is the largest of the eight university medical centers in the Netherlands, both in terms of turnover and number of beds. The Erasmus MC ranks #1 of the top European institution in clinical medicine and #20 in the world according to the Times Higher Education rankings.
ErasmusMC offers 2-4 week personalized medicine internships illustrating the power of molecular diagnostics followed by targeted treatment strategies.
During the internship complex genetic cases will be discussed to illustrate the variable clinical presentation linked to specific perturbed molecular pathways underlying auto-immune and auto-inflammatory disorders.
The intracellular metabolism in monocytes, macrophages and dendritic cells (DCs) appears crucial for the function of these critical controllers of innate and adaptive immunity. They undergo profound metabolic reprogramming in response to environmental cues, such as hypoxia or nutrient alterations, but also upon triggering by danger signals and cytokines. Therefore, metabolic alterations in monocytes, macrophages and DCs appear crucial to maintain immune homeostasis and metabolic dysregulation could lead to disease pathology. You will be part of a multidisciplinary team comprising of internists, pathologists immunologists, molecular biologists and bioinformaticians studying patients suffering from auto-immune and or auto-inflammatory disorders.
Accommodation
Try Airbnb in Rotterdam
Fees and Program Logistics
This program has the following durations available:
| Duration | Fee |
|---|---|
| 2 weeks | $875.00 |
| 4 weeks | $1,500.00 |
This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.
Who Can Apply
All physicians and biomedical scientists from around the world can apply
Host Details
Host Name: Prof. Dr. Ing. Peter J. van der Spek
Affiliation: ErasmusMC
Address: Doctor Molewaterplein 40, 3015 GD Rotterdam, Netherlands
Website URL: https://www.erasmusmc.nl/
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.
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Onsite/On-Campus Program
Fellowship - Basic/Translational/Clinical Research Program
Netherlands
Application Review Deadline:
Dec 1st, 2024
Reviews
Program Logistics and Administrative Fees
This program has the following durations available:
| Duration | Fee |
|---|---|
| 2 weeks | $875.00 |
| 4 weeks | $1,500.00 |
This program allows Merit Applications. This program allows merit-based applications for virtual and onsite clinical and research programs. If you are successfully awarded under this category, Trialect or the host mentor will cover the tuition fee only. All applications will be evaluated based on merit. Due to the high level of competition, the chances of being selected under the merit category are quite limited.
Who Can Apply
All physicians and biomedical scientists from around the world can apply
Host Details
Host Name: Prof. Dr. Ing. Peter J. van der Spek
Affiliation: ErasmusMC
Address: Doctor Molewaterplein 40, 3015 GD Rotterdam, Netherlands
Website URL: https://www.erasmusmc.nl/
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.
Questions and Answers
Commonly asked questions about this program from the host and other attendees.
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