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Endocrine Pathology Research Program

Department of Pathology at HUCA, Asturias, Spain

Main Areas of Interest

Molecular Bases of Thyroid Tumors: Exploring the genetic and molecular mechanisms underlying the development of thyroid cancers.
Oncocytic Tumors of the Thyroid and Endocrine Glands: Investigating the characteristics and pathogenesis of oncocytic tumors within thyroid and other endocrine glands.
Neuroendocrine Tumors and Familial Syndromes: Studying the link between neuroendocrine tumors and inherited syndromes to understand their genetic and clinical relationships.
Mutations in the DICER1 Gene: Researching how mutations in the DICER1 gene influence the occurrence and progression of endocrine tumors.

Techniques You Will Learn

Immunohistochemistry:

Theoretical and practical foundations of immunohistochemical techniques.
Diagnosis, prognosis, and monitoring of tumors from endocrine and neuroendocrine glands.
Familiarization with the selection and interpretation of immunohistochemical stains for endocrine tumors.

Molecular Biology Studies:

Indications for and interpretation of molecular biology techniques such as FISH (Fluorescence In Situ Hybridization) and PCR (Polymerase Chain Reaction) on samples from endocrine and neuroendocrine tumors.

Next-Generation Sequencing (NGS):

Indications for using NGS and interpretation of results.
Genetic counseling based on genetic findings.

Tumor Biomarker Testing:

Molecular testing to identify unique attributes of tumors, including genes, proteins, and other factors.
Application of molecular testing in determining treatment options.

Flow Cytometry:

Application of flow cytometry in research or clinical settings, as necessary.

Biobank Management:

Management of biological samples for biobanks, specifically focusing on endocrine and neuroendocrine tumor banks.

Curriculum

Fellows will receive comprehensive support to acclimate to their new environment, including assistance with finding suitable accommodation and local amenities, and registration at the University, where they will be issued an ID card. A desk space will be allocated to each fellow. A full induction covering safety, laboratory practices, and personal welfare will be conducted by the University's designated staff and myself.

I will schedule an initial meeting with the fellow to discuss the objectives of the training and the expected mechanisms for their fulfillment. We will then develop experimental plans with realistic timelines.

Fellows will receive thorough training to conduct each experiment and will be allowed to independently perform the experiments under supervision during their initial attempts. They will have the opportunity to engage with me and other laboratory members to discuss any aspect of laboratory operations or to seek clarification on specific protocols. Training will also be provided on how to analyze and interpret their data. Regular meetings, either weekly or bi-weekly, will be arranged to discuss their progress, reflect on findings, and plan subsequent experiments. Fellows are expected to maintain accurate and comprehensive records of their work in the laboratory books provided.

Fellows will also have the opportunity to participate in research group meetings and other academic activities within the School and the University. This includes attending bespoke workshops tailored to research career development, such as manuscript writing, grant writing, and networking. Additionally, they will be encouraged to orally present their work at least once in a research group meeting before the conclusion of their visit.

Toward the end of the training, I will meet with the fellow to discuss plans for publishing their work, if sufficient data has been collected, or for disseminating their findings at future conferences. They will be guided in identifying global or local opportunities for which the training has prepared them, enhancing their competitiveness and integration of the skills and knowledge acquired into their ongoing research or professional roles.

Throughout the training, any particular challenges or specific requests from the fellows will be fully considered to ensure that a responsive, relevant, and adequately structured training plan is developed.

Accommodation

1-Apartamento Europa Jardín (cheap apartment, good quality): Set in Oviedo, Apartamentos Europa
Jardín provides accommodations within 1.3 mi from Oviedo Cathedral. Free WiFi is available.
The units have parquet floors and include a seating area with a flat-screen TV, a fully equipped kitchen,
and a private bathroom. A dishwasher and coffee machine are also provided.
Plaza de la Constitución is 1.6 mi from the apartment. The nearest airport is Asturias Airport, 29 mi from
Apartamentos Europa Jardín.
Website (possible online reservation): https://www.aparteuropa.es/

2-ApartHotel Campus (cheap hotel, good quality): Located in the business and commercial center the
Aparthotel features modern facilities and stylish, well-equipped, contemporary accommodations in a
convenient location, with great access to the region’s major road network.
Website (possible online reservation): https://www.aparthotelcampus.es/

Fees and Program Logistics

This program has the following durations available:

Duration	Fee
2 weeks	$875.00
6 weeks	$1,500.00
12 weeks	$2,750.00

This program allows Merit Applications. If you successfully are awarded a merit application - Trialect will take care of all bench and service fees, but you will have to take care of travel and accommodation. All applications will be scrutinized under the merit category. Considering 50 million health professionals around the world, the chances of getting selected under the merit category would be very low.

Who Can Apply

All students interested in endocrine pathology

Host Details

Host Name: Severino Rey

Affiliation: Department of Pathology at HUCA, Asturias, Spain

Address: Av. Roma, s/n, 33011 Oviedo, Asturias, Spain

Website URL: https://www.researchgate.net/institution/Hospital_Universitario_Central_de_Asturias2

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.