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Unlocking Urologic Oncology Innovation QuickFire Challenge

Johnson & Johnson

Overview

As our population ages, the incidence of bladder and prostate cancers (commonly known as Genitourinary or GU cancers) continues to increase. Newer, more effective and less-invasive treatment options must be made available to help meet the needs of patients living with these growing diseases.1

Despite recent therapeutic achievements, including systemic immunotherapies, antibody-drug conjugates, and next-generation robotic surgical tools, additional scientific discovery is needed. This unmet medical need is not just a challenge—it is an invitation to innovate, by harnessing the power of cutting-edge research, interdisciplinary collaboration, and bold thinking to potentially reshape the future of Urologic cancer treatment.

As we look to a future where every patient, regardless of their cancer’s complexity, finds an effective treatment, Johnson & Johnson, together with the American Urological Association (AUA), has launched the Unlocking Urologic Oncology Innovation QuickFire Challenge. Innovators from across the globe are invited to submit their transformative potential solutions to improve treatment and care of patients with Bladder and Prostate Cancers.

The innovators with the best idea(s) will have the opportunity to receive grant funding from a total pool of up to $300,000, virtual access to the Johnson & Johnson global incubator network, JLABS, and mentorship from experts across Johnson & Johnson.*

*Subject to terms and conditions of applicable QuickFire Challenge and execution of an award agreement

Why this challenge matters to us

At Johnson & Johnson, we are committed to tackling the most critical healthcare challenges to improve patient care. Within the Genitourinary space, we recognize that Bladder and Prostate Cancers are impacting patients disproportionately.1

Building on our commitment to championing transformative innovation and our legacy of engagement with the American Urological Association, including as a founding member of the AUA Clinical Trial Consortium (AUACTC) and AUA Innovation Nexus Founders’ Circle advisory board, this QuickFire Challenge is an opportunity to support the next generation of innovation in urology.

What we’re looking for

Innovators from across the globe are invited to submit transformative potential solutions to help improve treatment and care of patients with Bladder and Prostate Cancers. Specific areas of interest include:

Therapeutics:

Treatment modalities that limit systemic and on-target, off-tumor toxicities, including local delivery
Provide organ-sparing treatment options for patients (with advanced disease)

Surgery:

Focal therapies including but not limited to local energy delivery
Technologies that improve upon endoscopic procedures such as trans urethral resection of bladder tumor (TURBT)

Awards

Timeline

April 25, 2025

Launch

October 3, 2025

Application deadline

Q1 2026

Award announcement

AI Based Application Success Predictor

🎯 1. Alignment with Strategic Focus & Unmet Medical Needs

Whether you're applying to QuickFire Challenges, JLABS residency, or disease-specific innovation grants, your proposal must address a clear, unmet clinical or market need in areas J&J prioritizes (e.g., oncology, metabolic disorders, health equity) 

Applications should directly link to J&J’s health equity, prevention, interception, or cure strategies

🌟 2. Transformational Innovation with Clear Milestones

J&J favors transformative science or technology that is not just innovative but also scalable and impactful 

Judges want a 12–18 month project plan with concrete deliverables and clear “time-to-market” goals 

👥 3. Strong Team & Institutional/Diverse Partnerships

Show a solid team with relevant expertise, including leadership, technical competence, and financial capacity 

For Innovation Grants or disease-specific awards (e.g., AACR-J&J Lung Cancer Grants), multi-institutional teams (2–3 PIs across institutions) with clinical components are required .

Health Equity and Veterans Challenges emphasize lived experience and team alignment with communities.

💰 4. Realistic Budgeting & Use of Funds

Provide transparent, justified budgets—QuickFire grants typically cap at US $250–500K, with higher-end provided via programs like JLABS + QuickFire .

Expect documentation of funding sources, existing partnerships, and financial solvency .

🏢 5. Access to Ecosystem (JLABS & Mentorship)

Many awards offer residency at JLABS, mentorship, and ecosystem access—but applicants must demonstrate readiness for such integration .

The offering includes capital-efficient lab space and entrepreneurship support 

🧠 6. Clear Go-to-Market/Implementation Plan

Competitive proposals detail key milestones, scalability strategy, and time-to-market within a short timeframe .

Strong plans also outline clinical validation components, especially for oncology or therapeutic innovations 

🔎 7. External/Peer-Led Selection & Community Input

Evaluation panels often include external experts, including subject-matter specialists and community stakeholders .

Community-based challenges emphasize lived experience with reviewers assessing feasibility, impact, team quality, and scalability.

📋 Quick Reference Summary

Success Factor	Action Items
Strategic alignment	Map proposal to J&J priorities & clinical gaps
Innovation & milestone focus	Emphasize transformative potential & timeline
Team strength	Showcase leadership, partnerships, and experience
Budget clarity	Detail use of funds and funding sources
Ecosystem integration	Demonstrate fit for JLABS and mentorship support
Implementation plan	Define next steps, go-to-market, and validation
Peer/external review readiness	Prepare for scrutiny by experts and communities

🛠️ Pro Tips

Choose a fitting grant stream: QuickFire, disease-specific, health equity, or veterans initiatives.

Highlight unmet clinical or market need directly related to J&J’s innovation priorities.

Assemble a team early: consider cross-institutional and community-led collaborations.

Develop a detailed 12–18 month roadmap with milestones and go-to-market strategies.

Prepare a realistic, justified budget—including current funding and financial stability.

Engage with JLABS network early, showing readiness for incubation and mentorship.

Submit polished, non-confidential documentation—formatted to J&J’s application templates.

Tailor to reviewers: include both scientific experts and representatives of target communities.

Specialties

Cancer

Urology

Oncology

Eligibility Requirements

Potential solutions will be evaluated by a panel of reviewers on their ability to meet the following criteria:

Strategic alignment with QuickFire Challenge areas of focus
Potential impact for transforming treatment and care of patients with Bladder and Prostate Cancers
Consideration for enabling access across a range of healthcare settings including community clinics
Feasibility of the idea and supporting data
Demonstrated strong differentiation of potential solution and team’s approach
Team quality and capabilities

Sponsor Details

Sponsor Institute/Organizations: Johnson & Johnson

Sponsor Type: Corporate/Non-Profit

Address: New Brunswick, New Jersey, USA

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