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Sylvia Lawry Physician Fellowships

National Multiple Sclerosis Society

With the increasing number of new therapies being developed for use in MS, there is a need for physicians trained in conducting clinical trials. To this end, the Society established the Sylvia Lawry Physician Fellowship Program, named in honor of its founder. Clinical trials to test the safety and efficacy of therapies for multiple sclerosis are highly complex and require special expertise and knowledge to monitor this highly variable disease. This program provides the individual with an MD or equivalent medical degree with up to 3 years of formal training, under the tutelage of an established investigator, in key elements associated with conducting clinical trials in MS. Residents who have or will have received training in neurology or physiatry in the United States, and who are in the PGY3 or PGY4 stage or beyond, are eligible to apply.

AI Based Application Success Predictor

🧠 1. Direct Relevance to MS Mechanisms or Patient Impact

NMSS prioritizes research that targets:

Causes and mechanisms of MS (e.g., demyelination, neurodegeneration, inflammation)

Disease progression, repair, and neuroprotection

Symptom management (fatigue, mobility, cognition, spasticity)

Improved care delivery or quality of life

Strong predictor: Clearly stated MS relevance and a translational pathway to improve clinical outcomes.

🧬 2. Scientific Innovation + Rigor

Successful proposals are:

Hypothesis-driven, with specific aims

Designed with strong methodological rigor

Feasible within the scope, timeframe, and budget

Commonly funded approaches include:

Human immunology studies

MRI/imaging biomarkers

CNS repair & remyelination models

Clinical trials or pilot studies

Behavioral interventions & rehab

Predictor: Novel ideas backed by preliminary data or strong rationale, and clear, measurable objectives.

👩‍🔬 3. Experienced or Emerging MS-Focused Investigators

NMSS funds both:

Established researchers with a track record in MS or neurodegeneration

Early-career scientists with strong mentorship and MS research plans

Predictors include:

Prior publications or pilot data in MS or neuroinflammation

MS-focused mentors (for fellowships)

Evidence of a long-term commitment to MS research

🧑‍🤝‍🧑 4. Collaborative & Multidisciplinary Teams

Projects that bring together basic scientists, clinicians, rehab specialists, and engineers are highly valued

Cross-disciplinary integration (e.g., neuroimmunology + data science) improves funding chances

Predictor: A research team with diverse, complementary expertise and MS-relevant experience.

🧭 5. Alignment with NMSS Research Priorities

The Society prioritizes projects in these strategic focus areas:

Progressive MS (mechanisms, progression, repair)

Restoring function (rehabilitation, neuroplasticity, remyelination)

Stopping MS (immunological and viral triggers, early detection)

Improving quality of life (symptom relief, access to care)

Healthcare delivery & equity

Strong predictor: A direct match with one of these mission goals.

📋 NMSS Grant Programs

Program	Purpose	Typical Amount
Research Grants	Lab-based or clinical research on MS mechanisms, treatment, progression	~$150K–$750K
Pilot Research Grants	Preliminary studies to gather data for larger projects	~$50K–$100K
Career Transition Fellowships	Support postdocs moving to independence in MS research	~$550K over 5 years
Clinician Scientist Development Awards	Support MDs doing research	~$400K–$500K
Mentor-Based Postdoctoral Fellowships	Support for labs training future MS researchers	Varies
Health Care Delivery & Policy Research	Examines access, equity, and MS care systems	~$100K–$300K

✅ Strong Past Proposal Topics:

Remyelination therapies using iPSCs

Viral and environmental triggers in early MS

Gut microbiome and MS flares

Exercise effects on neuroplasticity in MS

Cognitive rehab using VR tools

Real-world care gaps in underserved MS populations

Specialties

Neurosciences

Eligibility Requirements

his program provides the individual with an MD or equivalent medical degree with up to 3 years of formal training, under the tutelage of an established investigator, in key elements associated with conducting clinical trials in MS.

Sponsor Details

Sponsor Institute/Organizations: National Multiple Sclerosis Society

Sponsor Type: Corporate/Non-Profit

Address: 733 3rd Ave 3rd Floor, New York, NY 10017

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