+ More Filters

Reset Filters

Title

Funding Organization

Funding Type

Eligible Country

Deadline

Other (Select all that apply)

Show Expired Programs

Show Verified Programs

Not Verified

Research Grant in Hereditary Disease Foundation

Hereditary Disease Foundation

The process of applying for funding for Research Grant starts with an applicant’s submission of an LOI through ProposalCentral between July 15, 2025 and September 3, 2025. On ProposalCentral, click ‘Apply Now’ to begin your LOI.

LOIs should have a direct application to Huntington’s disease. All LOIs related to Huntington’s disease are reviewed by a committee comprised of members of the SAB, who independently review and score each LOI. Only the LOIs that the SAB review committee considers the most impactful will have a full application requested.

HDF funds Research Grants at the post-graduate level. HDF grant and fellowship applicants must present a specific research plan. Please read the FAQs below before proceeding.

Grants provide more experienced researchers with seed funding to enable them to collect the preliminary data needed to obtain major, long-term funding from other organizations, including the National Institutes of Health. The Hereditary Disease Foundation awards one-year grants of $100,000. With (1) evidence of substantial progress and clear, compelling rationales for continuation; (2) a written request by the grantee for a one-year extension of the project as part of the grant progress report; and (3) competitive review by the HDF review committee, a subset of grants will be selected for the renewal for an additional year of funding of up to $100,000 (maximum possibility of one year renewal).

Key dates for 2026 applications

Letter of Intent Submission Dates
July 15, 2025 – September 3, 2025 (BY 11:59 PM ET)

Invitation to Submit Full Application
October 17, 2025

Application Deadline
December 2, 2025 (BY 11:59 PM ET)

Funding Decision
February, 2026

Start Date
March-April, 2026

AI Based Application Success Predictor

🎯 1. Laser Focus on Huntington’s Disease

All proposals must directly address HD mechanisms, biomarkers, disease modifiers, or therapeutic strategies.

LOIs are strictly screened for relevance—only the most compelling, HD-specific proposals move forward

2. Grants Tailored to Career Stage

Postdoctoral Fellowships:

2 years, $100K/year, for early-career scientists (≤7 years since PhD) committed full-time to HD research .

Requires a strong mentor letter.

Research Grants:

1-year, $100K for seed or pilot studies that generate data for larger funding

Career Advancement Grants:

Support transitioning postdocs to faculty in HD research.

Transformative Research Awards:

Multi-year, multi-million-dollar awards for high-risk, high-reward team science targeting new disease mechanisms .

3. Rigorous and Multi-Stage Review

A two-stage process:

LOI evaluated by the Scientific Advisory Board (SAB)—only HD-relevant, high-impact LOIs are invited to full application.

Full applications are reviewed by ≥3 experts with composite scoring; top proposals are discussed by the full SAB

Review criteria include:

Relevance, Novelty, Significance, Scientific Premise, Approach, Applicant Track Record, Environment, and Budget

4. High Scientific Standards & NIH Guidelines

Projects must include strong preliminary data, well-designed methodology (including power calculations), and rigorous experimental design.

Budgets must follow NIH-style formatting; no indirects (overhead costs are excluded)

5. Mentorship & Institutional Support

Fellowships and Career Awards require a mentor letter vouching for scientific independence, and institutional commitment is evaluated under “Environment” criteria .

6. No Outstanding Reports from Previous Grants

Applicants must have completed all progress reports on past grants before applying again

7. Full-Time Commitment for Early Career Awards

Postdoctoral Fellows must commit full-time effort to HDF-supported HD projects

8. Global Outreach & Team Innovation

HDF funds researchers worldwide and supports collaborative, transformative research that can reshape HD science or therapeutics

✅ Summary Table

Predictor	What to Do
HD-Specific Focus	Clearly address Huntington’s disease
Career-Stage Fit	Apply to fellowships, grants, or awards appropriate to your career
Data & Methods Rigor	Use pilot data, power calculations, and NIH design standards
Strong Mentorship	Secure a mentor letter emphasizing independence
Institutional Environment	Demonstrate support with resources and ethics
Clean Reporting Record	Ensure all past grant reporting is up to date
Budget Compliance	Use NIH styles and exclude indirect costs
Two-Stage Excellence	Invest in both a strong LOI and full proposal

🔧 Pro Tips

Start early — LOI deadlines are typically early September; full applications in December

Tailor your narrative — highlight why HD is the right model, include pilot data, and show collaborative potential.

Follow NIH formats — especially for budgets and biosketches.

Explain your HD-specific impact — show how your work could open new therapeutic avenues.

Collaborate — even solo grants benefit from highlighting multidisciplinary or multi-institutional input.

Address all review criteria — ensure you cover relevance, novelty, approach, applicant, environment, and budget.

Specialties

Genetics & Genomics

Eligibility Requirements

Applicants with overdue progress reports will not be permitted to submit new grant proposals until all delinquent reports have been received and reviewed.

Sponsor Details

Sponsor Institute/Organizations: Hereditary Disease Foundation

Sponsor Type: Corporate/Non-Profit

Address: 601 West 168th Street, Suite 54 New York, NY 10032 T 212 928 2121 F 212 928 2172 cures@hdfoundation.org

Legal & Affiliation Disclaimer

Affiliation Disclaimer: Trialect operates independently and is not affiliated with, endorsed by, or supported by any sponsors or organizations posting on the GrantsBoard platform. As an independent aggregator of publicly available funding opportunities, Trialect provides equal access to information for all users without endorsing any specific funding source, content, organization, or sponsor. Trialect assumes no responsibility for the content posted by sponsors or third parties.

Subscription Disclaimer: Upon logging into Trialect, you may choose to SUBSCRIBE to GrantsBoard for timely notifications of funding opportunities and to access exclusive benefits, such as priority alerts, reminders, personalized recommendations, and additional application support. However, users are advised to contact sponsors directly for any questions and are not required to subscribe to engage with funding opportunities.

Content Ownership and Copyright Disclaimer: Trialect respects the intellectual property rights of all organizations and individuals. All content posted on GrantsBoard is provided solely for informational purposes and remains the property of the original owners. Trialect does not claim ownership of, nor does it have any proprietary interest in, content provided by third-party sponsors. Users are encouraged to verify content and ownership directly with the posting sponsor.

Fair Use Disclaimer: The information and content available on GrantsBoard are compiled from publicly accessible sources in alignment with fair use principles under U.S. copyright law. Trialect serves as an aggregator of this content, offering it to users in good faith and with the understanding that it is available for public dissemination. Any organization or individual who believes their intellectual property rights have been violated is encouraged to contact us for prompt resolution.

Third-Party Posting Responsibility Disclaimer: Trialect is a neutral platform that allows third-party sponsors to post funding opportunities for informational purposes only. Sponsors are solely responsible for ensuring that their postings comply with copyright, trademark, and other intellectual property laws. Trialect assumes no liability for any copyright or intellectual property infringements in third-party content and will take appropriate action to address any substantiated claims.

Accuracy and Verification Disclaimer: Trialect makes no warranties regarding the accuracy, completeness, or reliability of the information provided by sponsors. Users are advised to verify the details of any funding opportunity directly with the sponsor before taking action. Trialect cannot be held liable for any discrepancies, omissions, or inaccuracies in third-party postings.

Notice and Takedown Policy: Trialect is committed to upholding copyright law and protecting the rights of intellectual property owners. If you believe that content on GrantsBoard infringes your copyright or intellectual property rights, please contact us with detailed information about the claim. Upon receipt of a valid notice, Trialect will promptly investigate and, where appropriate, remove or disable access to the infringing content.

View Funding Opportunity

Grant

Letter Of Intent Deadline:

Sep 03, 2025

Final Deadline:

Dec 02, 2025

Funding Amount:

$100,000

Questions and Answers

Commonly asked questions about this funding opportunity from the host and other attendees.

What is the grant reporting eligibility policy?

To maintain the integrity and effectiveness of our funding programs, the Hereditary Disease Foundation requires timely submission of all grant progress reports. Reporting Requirement for Continued Funding: Investigators who have not submitted required progress reports for previously funded grants will not be eligible to receive subsequent funding. All outstanding reports must be submitted and approved before any new funds are disbursed. Eligibility for Future Applications: Applicants with overdue progress reports will not be permitted to submit new grant proposals until all delinquent reports have been received and reviewed. Review of Current Applications: The review process for any current grant applications will be placed on hold until all outstanding progress reports from prior awards are submitted.

How are Postdoctoral Fellowships and Grants reviewed?

The Hereditary Disease Foundation Scientific Advisory Board sets the scientific priorities of the Foundation, reviews fellowship and grant applications, and selects the most impactful research projects for funding. The SAB is comprised of over thirty of the world’s leaders in basic science and clinical research, and includes clinicians specialized in Huntington’s disease, and leading scientists from the biotech and pharmaceutical industry. Former and current members of our SAB include Nobel Prize recipients, National Academy of Science members, Royal Society members, American Academy of Arts and Sciences members, President’s National Medal of Science recipients, MacArthur Foundation Genius Prize recipients, National Institutes of Health Directors, National Genome Research Institute, NIH Directors, and Society for Neuroscience Presidents. Reviewers are selected from both the SAB and the wider scientific community for appropriate scientific expertise. Applications submitted by members of HDF’s SAB members are reviewed by external reviewers in addition to one HDF-associated reviewer.

What criteria are used to judge and score applications?

Each application is reviewed based on the following criteria: 1) RELEVANCE: Is the proposed project relevant to understanding fundamental disease mechanisms in Huntington’s disease or advancing disease-modifying therapeutics? 2) NOVELTY: Are the hypotheses, approaches, and expected findings novel? 3) SIGNIFICANCE: If the proposed study is completed, will it make conceptual advance in understanding HD pathogenic mechanisms? Is the work feasible and will it provide new knowledge or broadly useful new tools or datasets for the HD field? Will it provide innovative therapeutic strategies or candidate therapies for HD? 4) SCIENTIFIC PREMISE: Is the proposed study based on strong evidence derived from literature or preliminary data? 5) APPROACH: Is the proposed scientific plan appropriate and feasible for addressing the main question(s)? Are the methodologies established? Are the experiments rigorously designed with sufficient statistical power? Are the numbers of animals/subjects proposed adequate to draw sound conclusions? 6) APPLICANT: Is the applicant qualified in conducting and/or supervising the proposed study? Does the applicant have a track record in the research field relevant to the proposal? We encourage grant applicants to include up to 2 letters of support from a mentor who can speak to the independence and expertise of junior applicants and/or key collaborators. 7) ENVIRONMENT: Does the applicant’s institution provide sufficient support to ensure the proposed studies can be completed in an optimal and timely manner? Are the facilities and equipment made available to the applicant for the study? 8) BUDGET: Is the budget appropriate for the proposed plan? Is there budget overlap with applicant’s other ongoing grants. 9) NIH GUIDELINES: Grants should follow NIH formatting guidelines, which can be found here.

When can I apply for an HDF Grant or Postdoctoral Fellowship?

The Hereditary Disease Foundation accepts and reviews Letters of Intent and Funding Applications once each year. Please see Key Dates above for the most current key dates for Letters of Intent, Application deadlines, as well as review and decision dates. All dates are subject to change.

What funding is available?

Research Grants: Grants are up to $100,000 for one year for salary, supplies, equipment, and benefits. In general, our funding can be used to cover NIH-approved costs listed as directs (i.e. salary, benefits, equipment, supplies, publication costs, etc.). THE HEREDITARY DISEASE FOUNDATION DOES NOT PAY INDIRECTS (overhead costs). Those listed as co-investigators can request salary support. Investigators and co-investigators should each provide an NIH-style biosketch. Collaborators do not need to provide biosketches and cannot request salary support. Incomplete applications will be reviewed as submitted. Hyperlinks should not be used in the LOI or research proposal.