Summary: The fiscal year 2025 (FY25) Prostate Cancer Research Program (PCRP) Idea Development Award (IDA) supports new ideas that represent innovative approaches to prostate cancer research and have the potential to make an important contribution to the PCRP mission. All applications are required to address one or more of the FY25 PCRP Overarching Challenges.
Distinctive Features:
• New Investigator Category: In addition to Established Investigators, the FY25 PCRP Idea Development Award encourages research ideas from investigators in the early stages of their careers (i.e., within 10 years after completion of their terminal degree). Qualified New Investigators must identify a collaborator(s) experienced in prostate cancer research.
Funding Details: The Congressionally Directed Medical Research Programs (CDMRP) expects to allot approximately $22.1 million (M) to fund approximately 13 Idea Development Award – Established Investigator applications with total cost caps of $1.7M. The maximum period of performance is 3 years. The CDMRP expects to allot approximately $8.4M to fund approximately 4 Idea Development Award – New Investigator applications with total cost caps of $2.1M. The maximum period of performance is 4 years. It is anticipated that awards made from this FY25 funding opportunity will be funded with FY25 funds, which will expire for use on September 30, 2031. Awards supported with FY25 funds will be made no later than September 30, 2026.
CDMRP intentionally funds innovative, paradigm‑shifting research across the full pipeline—from basic discovery to clinical trials—that addresses critical gaps in health outcomes for service members and the public .
Team‑science mechanisms (e.g., Synergistic Idea Awards) require multiple PIs—each funded independently—not sub-awards, encouraging true synergy across disciplines and institutions .
Tier 1: Peer review assesses technical merit.
Tier 2: Programmatic review weighs scientific excellence alongside program relevance, portfolio balance, and consumer advocate perspectives—consumers have equal voting power .
CDMRP includes nested awards for predoctoral, postdoctoral, and clinician-scientist candidates, with programs like the Ovarian Cancer Academy offering mentoring, networking, and skill-building .
Each program is guided by yearly appropriations and congressional mandate. Success depends on tightly aligning proposals with specific program objectives and anticipated topics .
RFAs are brief and often come with 30–60 days lead time. Staying alert to pre-announcements, registering in eBRAP and Grants.gov, and planning early are essential .
CDMRP actively coordinates with NIH and VA to prevent redundant funding. Before submitting, check existing programs and anticipate strategic adjustments to your proposal if overlap is flagged .
Core Factor | Why It Matters |
---|---|
Bold, high‑impact science | CDMRP rewards innovation and high risk |
Team/consortia readiness | Mechanisms favor multi‑PI, multi-institution studies |
Consumer inclusion | Proposals must speak to patient relevance and include advocates |
Mentoring and training plan | Especially for early- and mid-career awards |
Strict alignment with program scope | Tailor aims to each RFA and congressional intent |
Rapid response capability | Be ready to mobilize within 1–2 months |
Portfolio awareness & distinctiveness | Show how your proposal complements—not duplicates—other programs |
Track pre-announcements—sign up for CDMRP alerts and maintain your eBRAP profile.
Review recent funded summaries—understand what CDMRP programs value and shape your proposal accordingly.
Plan and build consortia early—ensure collaborators are involved from concept development to submission.
Engage consumer advocates—integrate patient or stakeholder perspectives in your aims and review process.
Check overlap and coordinate—avoid redundancy with NIH/VA programs; emphasize unique CDMRP-relevant aspects.
Prepare for fast turnarounds—have draft aims, compliant budgets, and institutional approvals ready to go.
Leverage nested training/career awards—if eligible, use them to build capacity and complement your full proposal.
🔧 Final Thought
CDMRP funding favors bold, multidisciplinary teams tackling high-priority challenges with consumer engagement, aligned to congressional mandates, and ready for rapid deployment. Proposals that demonstrate these qualities—and address career development—are strongly positioned to win.
2.1.1. Organization Extramural and intramural organizations are eligible to apply, including foreign and domestic organizations, for-profit and nonprofit organizations, and public or private entities.
Extramural Organization: An eligible non-Department of Defense (DOD) organization. Examples of extramural organizations include academic institutions, biotechnology companies, foundations, federal government organizations other than the DOD (i.e., intragovernmental organizations), and research institutes.
Intramural DOD Organization: Refers specifically to DOD organizations including DOD laboratories, DOD military treatment facilities, and/or DOD activities embedded within a civilian medical center.
Each investigator may be named on only one FY25 PCRP Idea Development Award application as a Principal Investigator (PI).
Although a PI may be eligible for both the New Investigator and Established Investigator categories, only one category may be chosen; the choice of application category is at the PI’s discretion
• New Investigator
By the application submission deadline date, the PI must:
○ Have the freedom to pursue independent research goals without formal mentorship.
○ Have not previously received a non-mentored PCRP Award (excluding the Exploration – Hypothesis Development Award).
○ Be an independent, early-career investigator within 10 years after completion of their terminal degree (excluding time spent in residency or on family medical leave). Time spent as a postdoctoral fellow is not excluded. Lapses in research time or appointments as denoted in the biographical sketch may be articulated in the application.
○ New Investigators working within a laboratory team are eligible to apply for this award provided they can demonstrate that they have the freedom to pursue independent research goals without formal mentorship. Graduate students and junior postdoctoral fellows with less than three years of postdoctoral training by the application submission deadline are not eligible for this award.
Investigators named as PI under the New Investigator category must confirm eligibility in Attachment 8, Eligibility Statement and independence, if applicable, in Attachment 9, Statement of Independence.
• Established Investigator
○ Independent investigators at all levels are eligible. Individuals affiliated with an eligible organization are eligible to be named as PI regardless of ethnicity, nationality, or citizenship status.
Sponsor Institute/Organizations: Congressionally Directed Medical Research Programs
Sponsor Type: Corporate/Non-Profit
Address: 1077 Patchel Street Fort Detrick, MD 21702-5024 Phone: (301) 619-7071
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Aug 08, 2025
Aug 29, 2025
$1,700,000
Affiliation: Congressionally Directed Medical Research Programs
Address: 1077 Patchel Street Fort Detrick, MD 21702-5024 Phone: (301) 619-7071
Website URL: https://cdmrp.health.mil/funding/pa/HT942525PCRPIDA_GG_v2.pdf
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