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Pathway to Stop Diabetes - Initiator Award (INI)

American Diabetes Association, Inc.

Award Term: Up to 7 years

Applicant Type: Postdoctoral Fellow

Maximum Funding: Up to $100,000 USD per year in Phase 1, Up to $325,000 USD per year in Phase 2

Indirect Costs: Up to 10% of direct costs in Phase 1, Up to 30% of direct costs in Phase 2

Principal Investigator Percent Effort Required: 75-100% effort in Phase 1, 50-75% effort in Phase 2

Citizenship: Authorized to work in U.S. or U.S. possessions

Application Submission Deadline: Wednesday July 23rd , 2025 at 5:00pm, Eastern Time

Initiator Award Description: This two-phased award is designed to support the transition of scientists from mentored training to independent research faculty.

Funding Support: Initiator Awards provide two distinct phases of research support: Phase 1 provides up to two (2) years of support for mentored training at a maximum of $100,000 USD per year (including 10% indirect costs). Phase 2 provides up to five (5) years of support for independent research at a maximum of $325,000 USD per year (including 30% indirect costs). The overall total combined support for Phase 1 and Phase 2 is $1,625,000 USD.

AI Based Application Success Predictor

1. Alignment with ADA Research Strategy

ADA favors investigator-initiated research that addresses diabetes prevention, treatment, complications, or cure professional.diabetes.org+15professional.diabetes.org+15professional.diabetes.org+15professional.diabetes.org+1diabetes.org+1.

Highest priority is given to proposals with the potential for high clinical or translational impact—especially those that can influence patient outcomes or public health practices .

🧬 2. Innovation & High-Risk/High-Reward Potential

Programs like Pathway to Stop Diabetes, Accelerator, and Initiator Awards aim to fund bold, original ideas with transformative potential diabetes.org+12professional.diabetes.org+12diabetes.org+12.

Reviewers look for compelling novelty—e.g., new interorgan communication mechanisms or tech-driven glycemic tools professional.diabetes.org+15diabetes.org+15diabetes.org+15.

👩‍🔬 3. Investigator Track Record & Career Stage

Early-career focus: strongest emphasis on postdocs transitioning to independence (Initiator) and junior faculty (Accelerator, Junior Faculty Development) investorshangout.com+4professional.diabetes.org+4diabetes.org+4.

Successful candidates show solid track records: publications, pilot data, prior grants—often leading to sustained funding and leadership positions diabetes.org+8professional.diabetes.org+8professional.diabetes.org+8.

📅 4. Commitment & Protected Time

Depending on the award, applicants must dedicate 75–100% effort during Phase I, and 25–75% in later stages professional.diabetes.org.

Institutional nomination and strong support are required—proposals can't be submitted individually professional.diabetes.org+3professional.diabetes.org+3professional.diabetes.org+3.

🌐 5. Mentorship & Institutional Support

Programs like Pathway pair awardees with world-renowned mentors to guide research and career development professional.diabetes.org+15diabetes.org+15diabetes.org+15.

Robust institutional backing—labs, resources, training environment—is essential .

📊 6. Expected Impact & Sustainability

Reviewers assess potential to move from preliminary data to independent funding or implementation.

A 2005 cohort supported by ADA had 85% securing further funding within 5 years diabetes.org+2diabetes.org+2professional.diabetes.org+2.

✅ 7. Strong Administrative Planning

Administratively, grantees must deliver on: progress reports, financial reports, final reports, and publication/patent disclosures professional.diabetes.org.

Timeliness and compliance in reporting strengthen credibility for future awards.

🏆 Top Predictors at a Glance:

Predictor	Why It Matters
Mission alignment	Projects must fit ADA’s priorities (impact, innovation)
Innovation & novelty	Bold, high-risk ideas are favored
Early-career readiness	Strong for Phase‑1 and transition-focused awards
Track record	Publications/pilot data signal feasibility & capability
Institutional/mentor support	Essential for project success and nomination
Protected effort	Ensures focus and deliverables
Post-award performance	Publications, further funding, compliance boost renewals

🔧 Pro Tips for Applicants

Tailor to mission – clearly link your project to ADA’s current strategic priorities.

Show novelty & impact – emphasize high-risk ideas with translational promise.

Highlight readiness – include strong publications and pilot data.

Secure support – institutional nomination, mentorship plans, and defined effort commitment.

Plan for sustainability – outline steps for future grant success.

Ensure administrative readiness – commit to timely reporting and compliance.

Specialties

Diabetes

Eligibility Requirements

Eligible applicants must currently be in research training positions (post-doctoral fellow, research fellowship) and have no more than seven years of research training following terminal doctoral degree. Applicants cannot concurrently hold an NIH K99/R00 grant. Candidates must be identified through institutional nomination; applications will be accepted only from individuals with the appropriate institution support.

Sponsor Details

Sponsor Institute/Organizations: American Diabetes Association, Inc.

Sponsor Type: Corporate/Non-Profit

Address: 2451 Crystal Drive, Suite 900 Arlington, VA 22202‑4804, USA

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