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Path to a Cure - Pilot and Feasibility Award

Cystic Fibrosis Foundation

Program Name: 2025 Spring Path to a Cure (PTAC) Pilot and Feasibility Award

Brief Program Overview/Description: Path to a Cure: Pilot and Feasibility Awards are intended to support projects that will develop and test new hypotheses and/or new methods that could eventually contribute to the development of a cure for Cystic Fibrosis (CF) and to support promising new investigators as they establish themselves in research areas relevant to cystic fibrosis. The intent of these awards is to enable investigators to collect sufficient data to compete successfully for support from the NIH or other funding agencies.

Pilot and Feasibility studies that may be high risk but high reward when it comes to advancing our understanding of the disease or developing technologies that can advance us towards a cure are encouraged to apply through this mechanism. Applications for continued funding of a project, or long-term support of an investigator, will not be considered through this program. Projects that are an extension of previous work should be submitted through the Path to a Cure: Research Grant mechanism.

Proposals should focus on topics such as restoration of CFTR protein function or approaches to fix/replace the defective CFTR gene. Applicants seeking to submit proposals focused on topics such as mucociliary clearance and airway hydration, infection and inflammation, or non-lung manifestations of disease should apply through the Pilot and Feasibility Award mechanism. Applications for continued funding of the same project, or for long-term support of an investigator, will not be considered.

Specialties

Others

Pulmonology

Eligibility Requirements

• United States residents and applicants from outside the United States are welcome to apply.

• Applicants must be independent investigators (an individual who is out of fellowship training and whose institution allows them to submit applications for research funding as a Principal Investigator).

o Candidates who are clinical fellows should apply to the CFF Clinical Fellowship program for the appropriate year.

o Candidates who are postdoctoral fellows should apply to the CFF Postdoctoral Research Fellowship program.

• Applicants from for-profit organizations should speak to the Program Officer about eligibility before applying through this mechanism.

• Additional eligibility requirements can be found in Section IV and Section VI (Goals of Research) below.

Sponsor Details

Sponsor Institute/Organizations: Cystic Fibrosis Foundation

Sponsor Type: Corporate/Non-Profit

Address: 4550 Montgomery Ave. Suite 1100 N Bethesda, MD 20814

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