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Osteosarcoma restricted funding call

Bone Cancer Research Trust

Since the Bone Cancer Research Trust was formed in 2006, we have awarded over £11 million to research focused on improving outcomes for primary bone cancer patients. To date, we have funded 220 research grants and continue to expand our research network, encouraging more researchers to focus their expertise on primary bone cancer.

Osteosarcoma restricted funding call

Treatment for osteosarcoma has not changed for several decades and still relies on a cocktail of toxic chemotherapies. New, targeted treatments, with fewer immediate and long-term side effects are desperately needed to ensure that more patients survive and thrive after treatment.

The Bone Cancer Research Trust & Hannah’s Willberry Wonder Pony Charity are committed to driving improvements through the funding of high impact, innovative and collaborative research.

The charities are delighted to be working together to offer funding of up to £250,000 to support clinical or translational projects focused on improving outcomes for osteosarcoma patients.

Funding is available to researchers and/or clinicians working in an academic or clinical institution in the UK, however, international collaboration is encouraged where appropriate. As part of this funding call, we welcome applications for funding to support translational research projects up to a maximum value of £250,000.

The proposals should demonstrate a clear line of sight to patient benefit and be both hypotheses driven and generating. They should clearly describe background evidence (including figures) and previous publications that have been used to support the submitted project, how the described experimental design will answer the questions posed in the project and how research may lead to patient benefit. Patient involvement in the development of applications will be expected. The Bone Cancer Research Trust has a Patient & Public Involvement Panel (PPIP) and we are able to facilitate engagement between members and researchers. If you would like to seek the input of PPIP in the development of your proposal, please email us at research@bcrt.org.uk by Friday 13th June 2025.

All costings will be fully scrutinised, and so clear justifications should be included.

Timeline

Grant call opening: 11th April 2025

Call closing: 11th July 2025

Award expected in December 2025

AI Based Application Success Predictor

🎯 1. Patient-Focused, Hypothesis-Driven Impact

BCRT prioritizes projects with a clear line of sight to improving primary bone cancer patient outcomes—from hypothesis-based discovery to clinical/translational impact .

Epidemiology or quality-of-life studies are not within scope—this keeps the focus sharply on biological and treatment advances .

👩‍🔬 2. Inclusive Career-Stage Funding

Funding spans all career levels, with targeted opportunities:

Idea/Idea Grants (~£35K) for early-career or pilot work

Explorer Grants (~£70K) for advanced, multi-institution work

Studentships (~£170K) and Fellowships for PhD/postdoc training .

Skills Development Grants (up to £3K) support conferences or lab exchanges industry-wide .

🤝 3. Emphasis on Collaboration & Capacity Building

Larger grants (Explorer, clinical/translational) expect multi-institutional teams, especially combining UK and international partners .

BCRT actively nurtures early-stage researchers, encouraging pilot studies leading to larger-scale funding.

🧪 4. Strategic Fit into 2022–2032 Roadmap

Projects are favored if they support BCRT’s strategy: discovering causes, diagnostics, new treatments, tissue access, and ultimate translation.

Even calls specific to osteosarcoma or Ewing sarcoma require clear patient benefit and pilot potential .

🧑‍🤝‍🧑 5. Patient & Public Involvement (PPI)

Involvement of BCRT’s PPI panel in development (and review) is required—early inclusion with PPI demonstrates alignment with patient priorities .

🔍 6. Rigorous Peer-Review by ISAP

Applications undergo a multi-tiered process:

Eligibility & triage by BCRT staff

In-depth expert review (≥2 reviewers) + lay PPI review

Final ranking by the Independent Scientific Advisory Panel (ISAP), with input from peer reviewers and BCRT board approval .

BCRT provides anonymized feedback and allows resubmissions per policy.

💰 7. Budget Transparency & Justification

Detailed, well-justified budgets are critical—every cost is scrutinized.

Specific caps exist by grant type (e.g. £35K for Ideas, £70K for Explorer, up to £250K for clinical translational calls) .

✅ 8. Strategic Priority Outcomes

BCRT funds projects expected to lead to success in larger funding schemes from bodies like NIH or CRUK .

💡 Summary Table

Predictor	Suggested Strategy
Patient-focused applications	Build explicit clinical impact into proposal aims
Stage-aligned funding schemes	Match career level with the right grant (Ideas, Explorer, etc.)
Collaboration:	Partner across institutions, include both UK/international expertise
PPI inclusion	Engage the Patient & Public Involvement Panel early
Strategic translation themes	Tie projects to diagnostics, treatment, tissue access roadmap
Peer-review readiness	Prepare for multi-layered expert & PPI evaluation
Budget clarity	Justify all costs within grant-specific caps
Long-term funding pipeline	Frame proposals as stepping stones to larger awards

📈 Final Insight

Strong BCRT applications are those that offer innovative, collaborative, and well-justified research with immediate ties to improving primary bone cancer treatment. They should fit BCRT’s strategic roadmap, involve patient perspectives, and lay the groundwork for future funding success.

Specialties

Cancer

Orthopedics

Eligibility Requirements

Funding is available to researchers and/or clinicians working in an academic or clinical institution in the UK.

Eligible Countries:

United Kingdom

Sponsor Details

Sponsor Institute/Organizations: Bone Cancer Research Trust

Sponsor Type: Corporate/Non-Profit

Address: 10 Feast Field Horsforth Leeds LS18 4TJ 0113 258 5934

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