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Neoplastic Disease-AHNS/AAO-HNSF Young Investigator Research Development Award

American Head and Neck Society(AHNS)

The purpose of this award is to support a collaborative AHNS/AAO-HNSF research project by fostering the development of contemporary basic or clinical research skills focused on neoplastic disease of the head and neck among new full-time academic head and neck surgeons. The award is intended as a preliminary step in clinical investigator career development and is expected to facilitate the recipient’s preparation of a more comprehensive individualized research plan suitable for submission to the National Institutes of Health or comparable funding agency.

CONDITIONS Research supported by this award should be specifically directed toward the pathophysiology, diagnosis, prevention, or treatment of head and neck neoplastic disease, and may be either basic or clinical/translational in approach. Proposed projects shall be designed in collaboration with a preceptor investigator and approved by the candidate's department chairperson and institution. While not specifically required, proposals which aim to introduce new knowledge and methodology from other disciplines to research in head and neck disease, or which demonstrate collaborative effort with members of other related disciplines are encouraged. Projects must be designed so as to yield useful information within the period of award, but priority will be given to projects that are also innovative with promise to develop into new long-range or expanded research programs capable of attracting funding from other sources. Applications must be accompanied by a letter of support from the applicant’s Department Chair and Preceptor verifying that the applicant will be permitted to devote an appropriate amount of time to the conduct and timely completion of the proposed research project. Applicants must obtain letters of support/understanding from all key personnel on the project. The grantee must submit an interim progress report to the Foundation at the end of the first year of the award.

TERMS

1. Amount: $50,000 maximum ($20,000 in year 1, $30,000 in year 2)

2. Period: 24 months, non-renewable

3. Use of Funds: A detailed budget and budget justification constitute part of the application and will be evaluated as part of the review process. Funding may not be used to support the applicant’s normal salary during the period of the award. Allowable expenses include consultant fees (e.g., statistician); salary support for research assistants or other technical personnel; computer software or hardware; purchase and maintenance of experimental animals; and expenses related to publication of results, exclusive of reprint costs. Equipment and supplies purchased with this Award become the property of the recipient institution. Travel expenses may not be supported by this award. If university policy stipulates that a portion of this very modest award must go toward institutional indirect costs, no more than ten percent (10%) of the direct costs may be applied for indirect costs.

4. Review: Applications will be reviewed by members of the AAO-HNS Foundation Subcommittee on Research Grants and Prizes, four of whom are AHNS members. Recommendations for funding must be approved by the AHNS Research Committee and the AAO-HNS Foundation Board of Directors.

5. Notification: Letters of notification will be sent in June of the award year. Please do not call the AAO-HNSF office prior to that time to inquire about results.

6. Start Date: The recipient of the AHNS/AAO-HNSF Young Investigator Research Development Award will be announced publicly at the closest AAO-HNS Foundation Annual Meeting immediately following the award. The award may be activated as early as July 1 of the year of award, but no later than January 1 of the following year.

CAREER DEVELOPMENT GRANTS The AHNS/AAO-HNSF Young Investigator Award is a career development award. In addition to the a) Significance, b) Innovation, and c) Approach components of the Research Strategy, Career Development Award applicants must include: a) Candidate’s Background b) Career Goals and Objectives c) Career Development/Training Activities During Award Period d) Training in the Responsible Conduct of Research More information is provided in the Research Strategy instructions, which will be accessible after approval of Letter of Intent.

FORMAT Applications are in a similar format to the National Institutes of Health. All applications must be completed and submitted online through ProposalCentral™ at https://proposalcentral.altum.com. Visit http://www.entnet.org/core to begin the application process.

SIGNATURES The AHNS/AAO-HNSF Young Investigator Research Development grant is legally awarded to the institution with which the Principal Investigator is affiliated, not to the investigator or his/her Division or Department. For this reason, it is very important that applicants comply with their home institution’s policies on pre-submission processing of grant applications. This can take time, so it is wise to plan ahead, allowing adequate time for processing and approvals. Applicants are advised to consult their institution’s offices of research administration or sponsored projects for information on processing requirements for an application prior to its submission.

APPROVALS If the proposed research involves human subjects or vertebrate animals at any time, the project must be reviewed and approved by the appropriate Institutional Review Board (IRB) or Animal Care and Use Committee (IACUC). This approval should be obtained prior to submission and submitted with the application. If such approval is unavoidably delayed, enter “pending” instead of the approval date. Grant applications which are not supported by evidence of the appropriate IRB or IACUC approvals will not receive funding until such approval letters are submitted. In no case may the project start be delayed beyond January 1 of the year following the award. Any changes in the proposed work required by an IRB or IACUC to secure approval must be submitted to the Foundation with the follow-up certification, prior to review or after the work is in progress.

LETTER OF INTENT All applicants must submit a Letter of Intent online no later than 11:59pm, Eastern Standard Time, December 16, 2024. The Letter of Intent is completed online and includes the title of the project, the principal investigator, and an abstract of the work. This will facilitate planning review requirements. Visit http://www.entnet.org/core to begin the Letter of Intent process.

RECEIPT DATE Allow yourself enough time to have the appropriate individuals review your application. Once your application is complete, print your cover page and have all of the necessary individuals sign. Keep in mind that it may take a few days to obtain all of the necessary signatures. The CORE grants program is paperless, so no hard copies of the signature page are to be mailed. Once all signatures have been obtained, you should scan the document and upload the .pdf to the system and retain the original for your files if needed. Once the signature page has been uploaded, run the checks within the system and click ‘SUBMIT.’ You will receive a confirmation email indicating that your proposal has officially been submitted.

ALL materials must be submitted online by 11:59pm, Eastern Standard Time, January 15, 2025.

FOLLOW-UP In carrying out its stewardship of research programs, the AHNS or AAO-HNSF may request information essential to an assessment of the effectiveness of this program. Accordingly, the recipient is hereby notified that s/he may be contacted after the completion of the award for periodic updates on various aspects of employment history, publications, support from research grants or contracts, honors and awards, professional activities, and other information helpful in evaluating the impact of the program.

REPORTING REQUIREMENTS The Grantee is required to submit a final progress report thirty (30) days after the close of the project period, and a financial status report within ninety (90) days after the close of the grant period. While no verbal presentations or publications are required to result from this Award, any which do shall acknowledge the contribution of AHNS/AAO-HNSF Young Investigators Research Development Award. Recipients of the Award may be invited to present the results of their work at meetings of the American Head and Neck Society and/or American Academy of Otolaryngology-Head and Neck Surgery Foundation. The Award recipient is encouraged to use the results of the research program as pilot for the development of an application for a Clinical Investigator Award or First Independent Research Support Transition (FIRST) award from National Institutes of Health.

CONTACT If you have questions about this funding opportunity announcement, please contact Loren Hamilton (loren@ahns.info) at the American Head and Neck Society (AHNS) or the CORE Grants team (coregrants@entnet.org).

Specialties

Otolaryngology

Eligibility Requirements

Applicants for this award must:

• Be either an Otolaryngologist—Head and Neck surgeon, who are active members of the AAO-HNS. OR: Surgeons who are in head and neck fellowships or have completed a head and neck surgery fellowship and are active or candidate members of the AHNS. PLEASE NOTE: Medical oncologists and radiation oncologists are not eligible to apply for this award. • Be citizens of the United States, noncitizen nations, or have been lawfully admitted for permanent residency at the time of application.

• Have with demonstrated potential for excellence in research and teaching and serious commitment to an academic research career in head and neck surgery.

• Be sponsored by the Chair of his/her Division or Department and by an official representative of the institution which would administer the Award and in whose name the application is formally submitted.

• Are members or candidate members of the American Academy of Otolaryngology-Head and Neck Surgery and the American Head and Neck Society.

Priority will be given to fellows or junior faculty who have completed residencies or fellowships within four years of the application receipt date. Former ASHNS/AHNS or Foundation research grant recipients are eligible to compete for the AHNS/AAO-HNSF grant. Individuals who have already competed successfully for independent research grant support from a private or Federal funding agency are ineligible for this Award. Applications submitted by ineligible PIs will NOT be reviewed.