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Funding Opportunity




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MRFF National Critical Research Infrastructure Initiative - 2024 Clinical Trial Enabling Infrastructure

National Health and Medical Research Council


The 2024 Clinical Trial Enabling Infrastructure grant opportunity focuses on promoting development and implementation of ‘adaptive platform’ and ‘registry based’ clinical trials which are thought to offer more efficient evaluation of potential medical therapies over conventional trial designs.

This grant opportunity will provide grants of financial assistance across three streams, to support Australian medical research and medical innovation projects that:

  • Stream 1: address an area of unmet medical need by promoting the development and implementation of adaptive platform trials. Funding under Stream 1 is available as follows:
    • Topic A (Incubator): conducting inception projects that build evidence and capability to demonstrate the feasibility of establishing a national adaptive platform trial that would allow for rapid assessment of pharmacological and/or non-pharmacological interventions in an area of unmet need (up to $300,000).
    • Topic B (Targeted Call for Research): establishing a new national adaptive platform trial that addresses an area of unmet need, including set up of central infrastructure and conduct of initial launch domains (up to $5,000,000).
    • Topic C (Targeted Call for Research): expanding an existing adaptive platform trial by adding new domains that address an area of unmet need (up to $3,000,000).
  • Stream 2 (Targeted Call for Research): conduct a registry-based randomised controlled trial in an area of unmet medical need by embedding a registry-based randomised controlled trial into a pre-existing clinical registry (up to $1,500,000).
  • Stream 3 (Targeted Call for Research): establish a new clinical trial practice network or extend an existing clinical trial practice network to consolidate and strengthen sector capability in clinical trials and collaboration, with the aim of embedding evidence-based care in the health system and improving health outcomes, in an area of unmet medical need (up to $7,000,000).

 

Eligibility:

You can apply if you:

  • have an Australian business number (ABN)
  • are incorporated in Australia

And in accordance with s24 of the MRFF Act 2015, are one of the following entities:

  • a medical research institute
  • a university
  • a corporate Commonwealth entity
  • a corporation (including businesses and not for profits).

You can’t apply if you are:

  • an individual
  • a partnership
  • an unincorporated association
  • a trust (however, an incorporated trustee may apply on behalf of a trust)
  • a non-corporate Commonwealth entity
  • any organisation not listed in the eligible entity list
  • an organisation, or your project partner is an organisation, included on the National Redress Scheme’s list of Institutions that have not joined or signified their intent to join the Scheme
  • an employer of 100 or more employees that has not complied with the Workplace Gender Equality Act (2012)

An application may be submitted to one of the above three streams. 

An organisation may submit more than one application to a single stream, but there are restrictions on the number of applications an individual (Chief Investigator) may submit to a single stream.

To be considered for funding, 20% or more of all Chief Investigators must be early to mid-career researchers.

Find the full eligibility criteria in the grant opportunity guidelines.

Eligible Countries:

Sponsor Institute/Organizations: National Health and Medical Research Council

Address: National Health and Medical Research Council (NHMRC), Level 1, 16 Marcus Clarke Street, Canberra, ACT 2601

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Grant

Letter Of Intent Deadline:

Jul 17, 2025

Final Deadline:

Jul 17, 2025

Funding Amount:

$4,470,601

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