The Lupus Research Alliance (LRA) is the largest private funder of lupus research worldwide. The organization aims to transform lupus treatment while advancing towards a cure by funding cutting-edge, innovative research.
At present, therapy for lupus is mostly empiric and involves largely non-specific antiinflammatory and immunosuppressive agents. While these treatments are frequently beneficial, many patients do not respond adequately or suffer significant side effects. Importantly, even patients with low disease activity accrue organ damage over time. There are many unanswered questions regarding the pathogenesis of lupus. Thus, new conceptual and therapeutic approaches are urgently needed. To enable the development of more effective and safer lupus therapies, and to address major barriers in lupus research and translation, the LRA has established the Lupus Innovation Award (LIA).
PROGRAM DESCRIPTION The LIA provides up to $150,000 per year for up to two years. Early-stage investigators (ESIs) are eligible for a third year of funding (see Special Considerations section for further details). Both early career and established investigators new to lupus with highly innovative ideas are encouraged to apply.
The LIA supports pioneering, high-risk, high-reward approaches to major challenges in lupus research. The overarching goals of the LIA are to: (1) promote investigation of underexplored pathways and fundamental mechanisms of lupus and its complications and (2) initiate transformative discoveries in lupus that can drive the development of safer and more effective treatments or novel biomarkers. All studies should have a clear and direct relevance to people with lupus and should offer the potential to improve the standard of care for the disease or usher in a cure.
Individuals with a doctoral degree (MD, PhD, DO, or equivalent), holding a faculty, or equivalent, position and leading an independent research team at an academic, nonprofit, or government research institution are eligible to apply. US federal government research laboratories are not eligible for this award. There are no citizenship requirements for investigators applying to this program.
Applicants who have previously received LRA funding must also be up to date with all reporting requirements and other Terms and Conditions of the original award(s) at the time of applying.
The same research project may not be submitted for consideration to multiple LRA grant mechanisms in the same year. Such submissions will be triaged without review.
Continuations of long-term research projects are not appropriate for this grant mechanism.
Sponsor Institute/Organizations: Lupus Research Alliance
Sponsor Type:
Address: 270 Madison Avenue, Suite 300, New York, NY 10016
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Apr 02, 2025
Aug 04, 2025
$150,000
Affiliation: Lupus Research Alliance
Address: 270 Madison Avenue, Suite 300, New York, NY 10016
Website URL: https://www.lupusresearch.org/wp-content/uploads/2025/02/2025-LIA-RFA.pdf
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