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LLSC Blood Cancer Quality of Life Grant

The Leukemia & Lymphoma Society of Canada

The Leukemia & Lymphoma Society of Canada (LLSC) is Canada's largest voluntary health organization dedicated to funding blood cancer research, education and patient services. The mission of LLSC is to cure all forms of blood cancer and improve the quality of life of patients and their families. Since its founding in 1955, LLSC has invested millions of dollars for research specifically targeting blood cancers and continues to fund innovative research to advance more breakthrough therapies.
To this end, LLSC also supports community service programs, advocacy, and public and professional education.
LLSC supports research through the Blood Cancer Quality of Life Grant program
LLSC will provide funding up to a maximum of $75,000 per year for two years (up to a maximum total of $150,000 for the two years). Grant funding will be made in two annual payments.
Quality of life issues for blood cancer patients have been less well studied than other phases of care. There are many medical and non-medical consequences of treatments that vary with age, sex, gender, ethnicity, type of blood cancer, and treatment. Some cancer survivors experience few adverse effects once the active treatment phase is over, whereas others may experience a wide range of physiological, psychological and psychosocial effects that may continue for many years.
The intent of this funding opportunity is to support new research designed to address quality of life challenges experienced by Canadians affected by blood cancers. Quality of life cancer research has the potential to make a significant impact on the burden of disease in patients, survivors and caregivers.
The goal of the LLSC Blood Cancer Quality of Life Grant is to improve the health outcomes for blood cancer survivors of all ages from the time of their cancer diagnosis until the time of their death or entry into end-of-life care.
Diverse study types will be considered, including both interventional (e.g., feasibility, pilot, RCTs) and non-interventional studies (e.g., cohort, case-control, cross-sectional, measure development). Studies may include the use of quantitative, qualitative and mixed methods approaches to data collection and analysis.
Areas of focus may include, but are not limited to:
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Interventions of the emotional effects of cancer
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Interventions to address fear of recurrence
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Interventions or understanding of the acute and long term effects
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Vocational, finances and return to work

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Managing the chronic effects of blood cancers
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Development of quality of life measures specific to blood cancers
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Late effect prevention
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Interventions to optimize functioning in daily life
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Survivorship models of care
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Quality of life of specific populations (e.g., AYA, older adults, pediatrics, caregivers)
Funds for competitive applications will be awarded on the basis of scientific merit, using a priority rating, and will include evaluation of ethical research. The Scientific Review Panel (SRP) will review all applications. New investigators as well as established ones are encouraged to submit applications.

Definitions
Co-Principal Investigators, Co-Investigators, Collaborators, and Key Personnel:
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The Co-Principal Investigator is responsible for developing the Aims of the project.

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The Co-Investigator (who can also be referred to as Collaborator) is responsible for carrying out the Aims of the project.
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A Principal Investigator CANNOT be named as a Principal Investigator or a Co-Principal Investigator on another application during the same application cycle.
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A Principal Investigator can be listed as a Co-Investigator or a Collaborator on another application in the same cycle, without limit to the number of applications.
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A Collaborator or Co-Investigator can be named on more than one application or funded grant, without limit.
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Community Partners are patients or caregivers/family members of patients who have direct experience with the disease or intervention being studied but are not participants in the study that may be a part of the research project. Patient Partners can also be collaborators or co-investigators.

Specialties

Cancer

Healthcare Delivery

Oncology

Public Health

Clinical Trials

Hematology

Psychology

Eligibility Requirements

Researchers in any field are encouraged to apply but the proposal must directly address blood cancer.

The Principal Investigator (Principal Applicant) must be based in, or formally affiliated with, a Canadian non-profit Sponsoring Institution at the time funding commences and for the duration of the award. Applicants must hold a primary appointment that permits them to do independent research, supervise students, and publish their findings. Applications from non-academic facilities are not eligible. Applicants should hold a Ph.D., M.D., D.V.M. or equivalent degree.

The Application will require one Principal Investigator (PI) who is responsible for the preparation and submission of the proposal including the budget, the conduct of the research programs and adherence with all stipulations made by LLSC, the LLSC Policies & Procedures document, and the Grant Agreement, if funded. The Principal Investigator must be able to demonstrate a significant track record in the area of hematology and/or blood cancer research.

Investigators must demonstrate that their research environment is equipped and suitable for the proposed study; this includes demonstrated access to patient materials, where applicable. Collaboration between multiple investigators to strengthen the proposed research will be considered favorably, but is not a requirement.

The PI must be an independent investigator, which is defined as a scientist who has dedicated laboratory space, directly hires and supervises laboratory personnel (technicians, graduate students, postdocs and staff scientists) and makes all decisions concerning research activities and use of the grant funds. Individuals in the principal investigator role may not be a trainee or be in a subordinate position (i.e. directed or supervised by another), with respect to the subject matter of the proposed research/activities. Technical support personnel, postdoctoral fellows, research associates, Adjunct Professors, Status-Only Appointments, and investigators working outside of Canada are not permitted to apply as Principal Investigator.

For applicants who do not hold an eligible position, investigators can apply as Principal Investigators if they have a firm offer of an academic position (as described above) at an eligible Host Institution and the appointment is not dependent on the outcome of a pending application. However, the position must start by the grant's start date. In these situations, a letter from an authorized representative of the Host Institution is required, outlining the precise nature of the appointment (including the position title and main tasks), as well as the anticipated start date and duration of the appointment.
“Co-principal investigator” or “co-applicant” refers to a researcher who will be in charge of specific administrative and scientific aspects of the research project, whether or not that researcher has a formal relationship with the Host Institution. Adjunct professors and appointments that are for status only can fall under these categories. These individuals are not eligible to receive grant-funded salary support. Graduate students, postdoctoral fellows, research associates, technical support employees, and investigators working outside of Canada are not included under these categories.

A “collaborator” or “co-investigator” refers to individuals who will make substantial intellectual contributions to the research project or have contributed to the drafting of the application itself, but who are not eligible to be included as “Co-Principal Investigators” or “Co-applicants”. Students, postdoctoral fellows, research associates, lay contributors (including patient partners) and investigators based outside of Canada may be included in this category. Students, post-doctoral fellows and research associates may receive salary support from a grant.
Individuals who have been affected by cancer are considered community/patient/survivor/caregiver participants/partners. This category may include anyone who is at high risk of cancer, has been diagnosed with cancer, or provides physical and emotional care to someone with cancer but not in a professional or vocational capacity. Community partners and caregivers can act as “collaborators” or “co-investigators” depending on responsibilities and impact of contribution to the proposed project.

For any questions of eligibility or unusual circumstances not described above, please contact LLSC (paul.oconnell@lls.org).
A Principal Investigator may only submit ONE Application per application cycle and cannot serve as a Principal Investigator OR Co-Principal Investigator on more than ONE Application per cycle. A Co-Investigator (also known as Collaborator) CAN serve as Co-Investigator on more than one Application. A Principal Investigator or Co-Principal Investigator can serve as a Collaborator on other Applications (See Definitions below).

Eligible Countries:

Canada

Sponsor Details

Sponsor Institute/Organizations: The Leukemia & Lymphoma Society of Canada

Address: 2 Lansing Square, Suite 601, Toronto, ON M2J 4P8, Canada

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