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ISHLT Acellular Ex Vivo Lung Perfusion (EVLP) Research Grant

International Society for Heart and Lung Transplantation

The purpose of this grant is to fund research that aims to develop further advancements in acellular Ex Vivo Lung Perfusion (EVLP) technology. This could include various aspects, including optimization of perfusion techniques, intervention and repair strategies, immunomodulation and reconditioning, and outcomes research.

Grant Details

One grant of up to $37,500 will be awarded for one year.

Funding Stipulations / Grant Policies

Please review these guidelines and terms prior to completing your application. If you are ultimately awarded a grant, you will sign a letter of agreement (LOA) stating that you agree to these funding guidelines and terms, and the LOA will be co-signed by your institution’s grants/research office.

Research is anticipated to begin between January and December of the grant year.
b. Funding in the amount of $37,500 will be provided for the research project..
Funding will not be released until visa status is confirmed (if applicable).
The grant is intended to provide salary support for the researcher, other study personnel, statistical support, supplies/materials, animals, publication costs and travel related costs for abstract presentation and up to 10 percent of the grant can be used for institutional overhead. No other costs are permitted.
The grant will be paid in multiple installments to the recipient’s institution. First installment (50% of funds) will be paid at the beginning of grant work; the second installment (25%) will be paid mid-award (after receipt of a grant progress report) and the final installment (25%) will be paid after receipt of a final report.
Grant funding is generally not transferable from one recipient to another; transfer may be considered under compelling circumstances (e.g., the grantee leaves the institution and does not request a transfer of the grant, or the grantee requires an extended medical leave).
If the grantee relocates and requests to move the grant to the new institution, the ISHLT Grants and Awards Committee will determine if the grant can be transferred to the recipient’s new location, or if the grant must be surrendered and any remaining funds returned. If the grant is surrendered, a final report will still be required.
The applicant must acknowledge the grant as a funding source in all manuscripts and presentations derived from the funded research using the following statement: “This work was supported by a grant from Lung Bioengineer and the International Society for Heart and Lung Transplantation.” Copies of such publications must be submitted to ISHLT.
Pursuant to regulations of the federal Physician Payment Sunshine Act (included in the Affordable Care Act), NPI numbers will be collected from grant recipients (if applicable), and tax ID numbers collected from the recipients’ institutions (if applicable). All payments will be reported to the Centers for Medicare and Medicaid Services Open Payments system, as payments from ISHLT represent indirect transfers of value from the funding pharmaceutical company.
Reports are required at the following intervals depending on the term of the grant, and continuation of funding is contingent upon completion of these reports:
1. Mid-award progress report due six months after research start date.
2. Final report within 30 days of the conclusion of the grant term.
  1. A final report is required even if the grant is surrendered for any reason prior to the conclusion of the grant term.

AI Based Application Success Predictor

🧠 1. Early-Career Investigator Status with Track Record

Most grants target rising stars — junior faculty who have completed training within 3 years (for Career Development) or have begun their faculty position before grant start .

Applicants must demonstrate previous work in heart and/or lung transplantation, mechanical support, or heart failure .

🏥 2. Strong Institutional Affiliation & Resources

Eligible applicants must have an academic appointment at an accredited institution and demonstrate institutional support, such as lab space, faculty appointment letters (if still in training), and departmental backing .

📝 3. Active ISHLT Membership

Consistent membership in ISHLT is required throughout the application and funding period

🧪 4. Innovation & Relevance to Advanced Heart/Lung Care

Grants emphasize critical areas like mechanical circulatory support (MCS), transplantation, ICU care, biomarkers, AI tools, and biomarker validation .

Innovation challenge grants favor novel technologies—e.g., noninvasive dd-cfDNA, AI-based profiling, ex vivo lung perfusion

🎯 5. Feasible Plan & Translational Potential

Projects should be well-scoped with a realistic timeline, aiming to substantially impact clinical practice within 1–5 years .

Feasibility, including clear methodology and data endpoints, is critical .

💰 6. Budget Adherence & Proper Cost Allocation

ISHLT grants typically cover salary, supplies, statistical support, with strict limits (e.g., indirect costs ≤10%, no excessive overhead or equipment budgets) .

Funding is phased with milestones—e.g., Career Development grants disburse quarterly tied to reports .

🧑‍🔬 7. Peer Review Emphasizing Scientific Merit

Applications are evaluated by expert committees scoring aims, significance, innovation, approach, feasibility, and investigators’ track record .

✅ Key Strategies for a Winning Application

Factor	What to Emphasize
Early-career status	Position yourself as a rising faculty with a focused research trajectory.
Institutional support	Include faculty appointment, support letters, and resource descriptions.
ISHLT engagement	Maintain active membership and participation.
Clinical/scientific salience	Center on transplantation, MCS, biomarkers, AI, or cardiogenic shock.
Methodological soundness	Clearly outline study design, endpoints, and realistic timelines.
Budget discipline	Request only permitted expenses; follow funding structure and reporting schedule.
Strong presentation	Craft clear, concise aims; highlight innovation and capacity to deliver results.

🔁 Final Thoughts

To maximize your competitiveness, present yourself as a well-prepared early-career faculty member with:

A focused, innovative project in priority ISHLT areas (transplantation, MCS, biomarkers, AI).

Institutional backing through faculty appointment and resources.

ISHLT engagement and membership.

Sound methodology, realistic feasibility, and budgeting.

A scientific narrative ready for rigorous peer review.

Specialties

Cardiovascular Diseases

Pulmonology

Eligibility Requirements

Academic Appointment and Institutional Resources:

The applicant must either have an academic appointment or clinical appointment or may be in training at an accredited institution.
An individual who applies for a research grant while still in training must have been offered and accepted a faculty position that will begin on or before initiation of the grant OR submit a letter of institutional commitment from a division or department chair at the institution at which the research will be conducted, if still in training at initiation of the grant.

ISHLT Membership

The applicant must be an active member of ISHLT or have submitted a completed membership application by 30 September, 2024.

Previous ISHLT Funding/Funding from Other Sources

There are no restrictions on past or current funding.
- The applicant may be a past or current recipient of ISHLT funding including Fellowship or Faculty Development research grants.
- The applicant may currently hold career development awards, mentoring awards, or other independent research awards.
If the applicant is currently receiving funding for a project similar to the topics described in this request for applications, the applicant should explain how the funds of the grant would not overlap with the funds of the other research support.

Miscellaneous

Applicants who have a substantial relationship with Lung Bioengineering that would present a real or perceived conflict of interest if awarded this grant must first contact ISHLT to declare the conflict before submitting an application. Examples of a substantial relationship with an industry partner include board member, member of advisory council, consultant, lecturer, etc.
Employees of Lung Bioengineering cannot submit an application.
Upon disclosure, the Grants and Awards Committee will determine if the individual is eligible to submit an application and will notify the individual in a timely manner.

Sponsor Details

Sponsor Institute/Organizations: International Society for Heart and Lung Transplantation

Sponsor Type: Corporate/Non-Profit

Address: 141 West Jackson Suite 1340 Chicago, IL 60604 USA Phone: +1-312-224-1277

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