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Expanding Indications for Radiation Therapy in RADIATION ONCOLOGY
ABOUT ROI
The Radiation Oncology Institute (ROI) – the ASTRO Foundation – was established in 2006 as the philanthropic partner to ASTRO to accelerate research and education. Since then, the ROI has invested $4.7 million in bold and innovative ideas in radiation therapy to improve outcomes for patients so they can live longer, healthier lives. ROI issues an annual request for proposals (RFP) to catalyze discovery in a high priority area of research for radiation oncology by awarding grants to the best and brightest investigators. The RFP topic is selected with input from stakeholders across the radiation oncology community to identify the most pressing challenges that can be addressed through research.
BACKGROUND
There is increasing interest in expanding the use of radiation therapy to conditions other than cancer, including but not limited to osteoarthritis, ventricular tachycardia, tremors, and wet-type age-related macular degeneration. However, more research is needed to establish the efficacy of radiation therapy in these conditions and others to help more patients than ever live longer, healthier lives. For this specific Request for Proposals, priority will be given to proposals that will lead to expanding indications for radiation therapy. While not specifically excluded, benign conditions for which radiation therapy is already commonly used will have lower priority.
PURPOSE
Through this request, the ROI is seeking proposals for research on radiation therapy for the treatment of non-cancerous conditions. The long-term goal is to ultimately expand the indications for radiation therapy. Aims of the research project can include but are not limited to:
• Understanding the underlying mechanisms of the treatment
• Demonstrating clinical efficacy
• Facilitating implementation at a larger number of practices
• Generating evidence on cost and/or comparative effectiveness
• Developing educational materials for patients, caregivers and other medical professionals
• Advancing health equity and reducing disparities in care for underserved populations
In addition to expanding indications for radiation therapy, the proposed research should align with the overall ROI Mission and Vision.
Proposals should focus on the highest impact research questions for the field of radiation oncology and clearly demonstrate the potential for securing additional funding to continue the research trajectory. Projects resulting in tangible deliverables with practical applications for radiation oncology professionals and their patients such as decision support tools, educational materials, abstracts, and manuscripts will be given priority. Knowledge derived from these studies should aim to improve outcomes for all patients and transform practice.
AWARD AMOUNT
A typical budget for a project supported by this mechanism is expected to be limited to a total of $50,000 over 2 years. However, larger budgets will be considered with the firm limit that costs may not exceed $150,000. Special attention will be given to projects that demonstrate efficiency and economy of resources to pursue the research proposed. ROI will not pay indirect costs, but applicants should contact ROI at roi@astro.org if they could experience a hardship due to this policy. Each proposal’s total budget and how it fits into the ROI’s available funds will be part of the proposal’s evaluation. The number of grants in each funding cycle is not predetermined by ROI. Awards are made based on application merit and the availability of funds.
Grants may be approved for up to a two-year period. Funding for the second half of the award period is contingent upon submission and approval of an interim progress report. Projects must start by August 1, 2025 and end no later than July 31, 2027.
ROI encourages applications submitted by:
• Researchers from diverse backgrounds, including individuals who are members of populations that are currently underrepresented in biomedical research.
• The full range of eligible institutions, including those serving primarily underserved groups, those that may be less research-intensive, and from all domestic geographic locations.
HOW TO APPLY
All application materials must be submitted through ProposalCentral at: proposalcentral.com. Log in, click on the "Grant Opportunities" tab and select "Radiation Oncology Institute" in the "Filter by GrantMaker" drop-down menu. Applicants are encouraged to start their application early to complete all required components by the deadline, including institutional signatures. The “Validate” button can be used to generate a list of missing required elements at any time before submitting the application.
Specialties
Eligibility Requirements
• Qualified individuals from institutions and organizations in the radiation oncology (RO) community. Pre-doctoral students are not eligible.
• Applicants enrolled in residency programs or post-doctoral fellowships require a faculty mentor.
• Individuals from institutions and organizations of the non-RO community who possess necessary qualifications for specified research are eligible.
• At least one of the key personnel (Principal Investigator (PI), co-PI, faculty mentor) must be an ASTRO member at the time of application.
• The Sponsoring Institution that will receive and manage the grant funds must be a qualified 501(c)(3) organization or government-sponsored university in the United States or their equivalent in Canada.
Eligible Countries:
Sponsor Details
Sponsor Institute/Organizations: RADIATION ONCOLOGY INSTITUTE
Address: 251 18th St. South, 8th Floor Arlington VA 22202 Phone:703-502-1550 | Fax:703-502-7852
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Grant
Letter Of Intent Deadline:
Nov 22, 2024
Final Deadline:
Feb 14, 2025
Funding Amount:
$50,000
up to 150,000
Host Details
Affiliation: RADIATION ONCOLOGY INSTITUTE
Address: 251 18th St. South, 8th Floor Arlington VA 22202 Phone:703-502-1550 | Fax:703-502-7852
Website URL: https://www.roinstitute.org/research-and-education/grants-and-awards/funding-opportunities
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.
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