Program Title:
EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems (E-CORE)
Synopsis of Program:
The Established Program to Stimulate Competitive Research (EPSCoR) supports the U.S. National Science Foundation (NSF) mission by promoting nationwide scientific progress. Through this program, NSF fosters partnerships among academic institutions, government entities, industry, and non-profits. These collaborations aim to drive long-term improvements in research infrastructure, enhance R&D capacity, and boost the research competitiveness of eligible EPSCoR jurisdictions, including states, territories, and commonwealths.
A jurisdiction’s research ecosystem is the interconnected network of organizations, researchers, trainees, community stakeholders, and resources that contribute to the process of research and innovation that advances fundamental knowledge, generates use-inspired products, and ultimately cultivates beneficial impacts for a jurisdiction. E-CORE supports jurisdictions in building significant and sustainable research capacity and research infrastructure for targeted areas of focus, hereinafter referred to as “cores,” that underlie a jurisdiction's research ecosystem.
Based on the evidence-based and self-identified needs of a jurisdiction, the types of cores supported by E-CORE may include (but are not limited to) development, enhancement, and/or ensuring the sustainability of: research administration; research facilities and infrastructure (including cyberinfrastructure); STEM education (K-12) pathways; higher education pathways; early career investigator pathways; broadening participation; workforce development; national and global partnerships; community engagement and outreach; technology transfer; economic development; and use-inspired research pathways. E-CORE projects must be designed to support the sustainability of the research infrastructure cores beyond the award period. Projects will also support the development and growth of new jurisdiction-wide connections, and the leveraging of existing jurisdiction-wide connections, to drive substantive and sustainable impacts.
Award Information
Anticipated Type of Award: Cooperative Agreement
Estimated Number of Awards: 15
The number of awards granted annually is subject to the availability of funding. Multiple awards within a single jurisdiction will also be considered based on the availability of funds.
Projects may be funded for up to eight years, with an initial award for the first four years and the possibility of a renewal project award for four additional years based on project performance and the completion of project milestones. Each individual year’s continued funding will be contingent on satisfactory progress based on the annual reporting and progress toward implementing the strategic plan.
Anticipated Funding Amount: $37,500,000
An annual budget of up to $37.5 million is available to support up to 15 new E-CORE awards. The number of awards will depend on the availability of funds and the quality of submitted proposals.
Funding requests must be for a duration of four (4) years, with a maximum budget of $10 million total for the first four years and an optional renewal project award maximum budget of $8 million total for an additional four years. Within the maximum award budget, there is no restriction on the amount requested annually.
Note that in only rare and exceptional circumstances will no-cost extensions be granted during the initial or renewal project award period.
Who May Submit Proposals:
Proposals may only be submitted by the following:
- Institutions of higher education (PhD- and non-PhD-granting) that are accredited and operate a campus within the United States, its territories, or possessions, may submit proposals on behalf of their faculty.
- Distinct academic campuses within multi-campus systems (e.g., campuses that award their own degrees and have independent administrative structures, admissions policies, and alumni associations) qualify as separate submission-eligible institutions.
- Campuses that plan to submit a proposal through the Sponsored Projects Office of other campuses or organizations should contact NSF EPSCoR to discuss eligibility as early as possible and at least six weeks before submitting such a proposal.
- Non-profit, non-degree-granting domestic U.S. organizations, acting on behalf of their employees, that include (but are not limited to) independent museums and science centers, observatories, research laboratories, professional societies, and similar organizations that are directly associated with the Nation’s research or educational activities. These organizations must have an independent, permanent administrative organization (e.g., an office of sponsored research) located in the United States, its territories, or possessions, and have 501(c)(3) tax status.
- Jurisdictional/state governments, or agencies or commissions thereof, when coordinating efforts of multiple organizations within the jurisdiction.
- Tribal Governments with the governing body of any Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges to exist as an Indian tribe under the Federally Recognized Indian Tribe List Act of 1994 (25 U.S.C. 479a, et seq.) or Indigenous communities that are not recognized by the Federally Recognized Indian Tribe List Act of 1994 (25 U.S.C. 479a, et seq.).
E-CORE proposals may only be submitted by organizations within jurisdictions meeting the EPSCoR eligibility criteria.
E-CORE proposals may not be submitted by organizations that serve as the lead organization on an active E-CORE or RII Track-1 award unless that award is in its final year or under a no-cost extension and will not be renewed. However, individuals employed by said organizations may serve as funded project participants or collaborators in roles other than PI or co-PI in an E-CORE proposal submitted by another organization. Such engagement must not be duplicative of currently funded activities, including active EPSCoR RII awards.
E-CORE submissions should be multi-organizational, with a lead organization and additional collaborating partner(s), which may include academic and non-academic organizations.
Collaborations must be indicative of building or developing cores within the jurisdiction and an interconnected jurisdiction-wide network that is able to link research efforts to individuals in a jurisdiction’s research ecosystem.
NSF encourages the participation of Emerging Research Institutions as the lead organization and/or collaborative partners in E-CORE submissions:
- Emerging Research Institutions as defined in 42 §USC 18901 as institutions of higher education with an established undergraduate or graduate program that have less than $50,000,000 in Federal research expenditures within the year of the most currently available data;
Collaborations with other EPSCoR jurisdictions, non-EPSCoR jurisdictions, and international entities are allowed provided there is appropriate justification of how such collaborations will improve research infrastructure within the proposing jurisdiction in ways that cannot be achieved through collaborations within the jurisdiction. However, since EPSCoR program funds may only be allocated for activities and personnel within an EPSCoR jurisdiction, participation of collaborators in non-EPSCoR jurisdictions must be unfunded collaborators.
Who May Serve as PI:
Principal Investigators must hold at least 50% appointments in eligible organizations within an EPSCoR jurisdiction.
Each collaborating organization must be represented by a PI, co-PI, or other senior/key personnel.
Sponsor Institute/Organizations: U.S. National Science Foundation (NSF)
Sponsor Type: Government/Federal
Address: 2415 Eisenhower Ave Alexandria, VA 22314 (703) 292-5111
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Jul 15, 2025
Jul 15, 2025
$37,500,000
15 awards available.
Affiliation: U.S. National Science Foundation (NSF)
Address: 2415 Eisenhower Ave Alexandria, VA 22314 (703) 292-5111
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