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Early Detection and Diagnosis Project Award

Cancer Research UK

Key information

Career level

Early career researcher

Mid-career researcher

Established independent researcher

Clinician

Non-clinical researcher

Final submission

19 June 2025

Committee review

November 2025

Funding period

Up to 4 years*

Funding amount

Up to £500k*

Early Detection and Diagnosis Project Awards fund science to drive transformational change in how and when early cancers and pre-cancerous states are diagnosed.

Scientific remit

Early detection and diagnosis research seeks to detect and diagnose consequential precancerous changes and cancer at the earliest possible point at which an intervention might be made, reducing the burden of late-stage disease.

Early Detection and Diagnosis Project Awards will support discovery and translational/clinical research which is mindful of the clinical and population context.

The remit of these awards includes:

Identification and validation of early detection/diagnosis markers and understanding of disease trajectory
Identification of high-risk groups for early detection and diagnosis research and implementation
Data and computation-driven approaches to early detection/diagnosis
Development and use of appropriate preclinical model systems
Early detection/diagnosis technology development
Non-confirmatory clinical trials of early detection/diagnostic technologies or approaches
Health systems research for early detection/diagnosis
Research into clinician behaviour and decision support for early detection/diagnosis
Evaluation of impact of early detection and diagnosis policies and interventions
Research to understand and intervene in the behaviour of the public to enhance early detection and diagnosis
Research into the health economics of early detection and diagnosis of cancer

Early Detection and Diagnosis Project Awards may focus on any of these research areas, or any combination of them. All proposals should consider line-of-sight to clinical or population impact.

Early Detection and Diagnosis Project Awards are flexible in terms of duration and level of funding. Proposals may be at various stages of maturity dependent on technology readiness, novelty of the paradigm under investigation and availability of supporting data. Proposals should be composed and costed commensurately.

We particularly welcome applications that bring novel approaches from the fields of engineering and the physical sciences that could be applied to cancer detection and are mindful of potential clinical need, patient and population impact. As part of CRUK’s longstanding strategic partnership with the (link is external)Engineering & Physical Sciences Research Council (EPSRC)(link is external), there is an opportunity for any successful applications with relevant research components in these areas to be jointly supported by both CRUK and the EPSRC.

Out of remit

Proposals for research in these fields are likely to be ineligible for this funding scheme:

Research which does not have any line-of-sight to impact on early detection or diagnosis – this may be eligible for our discovery research funding opportunities
Research that focuses on population-level trials of screening approaches – this may be eligible for our Prevention and Population Research Committee

If you are unsure which funding scheme is most appropriate for your research, please get in touch to discuss your proposal.

What is funded

Awards are typically made up to £500k for up to 3 years, or 4 years when funding a PhD, and may be used to fund:

Postdoctoral researchers
PhD students (stipend, fees and running expenses)
Technical staff
Associated running expenses
Equipment

*The budgetary limit is indicative. Requests in excess of this should be discussed with the CRUK office before submission.

Cancer Research UK is also giving applicants of this funding scheme the opportunity to opt-in to a new multi-journal pilot project on Registered Reports

Specialties

Cancer

Eligibility Requirements

You should:

Have some postdoctoral experience or equivalent
Be scientists, clinicians or healthcare workers in UK universities, medical schools, hospitals, or research institutes

Multi-institutional proposals are welcome and awards can be held across institutions in the UK. Supporting roles (co-investigators/collaborators) from international and commercial organisations are welcome.

Sponsor Details

Sponsor Institute/Organizations: Cancer Research UK

Sponsor Type: Corporate/Non-Profit

Address: 2 Redman Place, London, E20 1JQ.

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