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Notice of Special Interest (NOSI): Research to Prevent Drug Use, Misuse and Addiction

National Institutes of Health

The National Institute on Drug Abuse (NIDA) is issuing this Notice to encourage grant applications in research on the prevention of risky drug use behaviors and addiction.While there has been significant progress identifying and intervening on risk and protective factors for substance use, population-level impact of substance use prevention interventions has not yet been achieved. There continues to be a need for development and testing of substance use prevention strategies across the lifespan and for population subgroups at greater risk.

NIDA is interested in?theory-driven prevention science?that spans intervention development and testing, as well as?services research, including dissemination and implementation science studies. Research?addressing?critical developmental?periods and transitions (e.g., transition to adulthood, transition out of foster care, job loss and housing instability, midlife/older adults) or targeting?interventions to?groups at increased risk of adverse outcomes (e.g., individuals with psychiatric co-morbidity, justice or child welfare-involved populations) is of priority. Intervention research may occur at any level (universal, selective, indicated, tiered), and across the lifespan.

NIDA prioritizes research that leads to the uptake and sustainability of effective practices and programs. To ensure interventions fit well into service settings, investigators are strongly encouraged to partner with stakeholders (e.g., those who the intervention is meant to benefit and those who will implement the intervention outside of a research study) at all phases of the intervention development and research process. NIDA is interested in interventions within a broad range of service settings, including justice, child welfare, social services, healthcare, education, and community settings. Finally, important to long term dissemination is the understanding of the economics of prevention. This may include intervention research that analyzes the costs of adopting evidence-based intervention strategies, studies of the costs relative to benefits of intervention delivery, and cost effectiveness research.

The research may include studies to:1) develop and test strategies to prevent the initiation of substance use, progression to substance use disorders,or to prevent substance use-related conditions such as HIV; 2) develop and test processes or strategies to implement, scale,and sustain evidence-based prevention in community, practice, and service systems;and,3) develop methods to conduct prevention science.Primary outcomes of interest for submitted applications include preventing initiation of substance use, misuse, and progression to disorder, as well as prevention of HIV infection.

This notice applies to due dates on or after June 5, 2022 and subsequent receipt dates through May 8, 2025.

NOT-DA-23-001

Specialties

Rehabilitation Medicine

Substance Use Disorders

Eligibility Requirements

This notice applies to due dates on or after June 5, 2022 and subsequent receipt dates through May 8, 2025.

Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) or any reissues of these announcements through the expiration date of this notice.

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type:

Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA

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