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Notice of Special Interest (NOSI): Investigations on Inborn Errors of Immunity/Primary Immunodeficiencies
The purpose of this Notice of Special Interest (NOSI) is to support research on the discovery and characterization of Inborn Errors of Immunity (IEIs), also referred to as Primary Immunodeficiencies, to understand the causes and mechanisms of disease, enable early detection and molecular diagnosis, and support the development of strategies to treat and eventually cure these disorders.
Innovations in whole genome sequencing and other high throughput technologies have led to more rapid discovery of novel genes and molecular pathways responsible for aberrant or sub-optimal immune responses, leading to enhancement of infection or other immune-mediated diseases. Identification of genes and pathways associated with IEIs should inform discovery and development of novel diagnostic methods to inform personalized approaches for therapies.
This NOSI will support research on the following topics of IEIs:
- Combined immunodeficiencies with associated or syndromic features
- Diseases of immune dysregulation
- Congenital defects of phagocyte number or function
- Defects in intrinsic and innate immunity
- Immunodeficiencies affecting adaptive immunity
- Autoinflammatory disorders
- Complement deficiencies
- Bone marrow failure
This notice applies to due dates on or after June 5, 2024 and subsequent receipt dates through March 16, 2027 .
NOT-AI-24-024
Specialties
Eligibility Requirements
Sponsor Details
Sponsor Institute/Organizations: National Institutes of Health
Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA
Grant
Final Deadline:
Oct 05, 2024
Funding Amount:
Varies
This program has not been verified by Trialect.
Host Details
Affiliation: National Institutes of Health
Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA
Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.
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