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Notice of Special Interest (NOSI): Immune Responses to Arthropod Feeding on Vertebrate Hosts

National Institutes of Health

This Notice of Special Interest (NOSI) solicits transdisciplinary research projects to understand 1) the immunologic events in the vertebrate host that occur at the bite site (skin) and systemically during and after feeding by hematophagous and ectoparasitic arthropods and 2) how immunologic events and vector salivary factors influence pathogen transmission and pathogenesis, impact induction or inhibition of protective immune responses, or cause allergic responses. Exploratory research on immune responses to arthropod blood feeding was formerly supported by the National Institute of Allergy and Infectious Diseases (NIAID) through the expired notice of funding opportunity (NOFO), PAR-18-860 , “Immune Response to Arthropod Blood Feeding (R21 Clinical Trial Not Allowed), and NOT-AI-21-059 , “Notice of Special Interest (NOSI): Immune Responses to Arthropod Feeding on Vertebrate Hosts.” The intent of this NOSI is to indicate continued NIAID interest for research in this area.

The purpose of this NOSI is to encourage multidisciplinary research to understand the immunologic events and/or introduction of vector salivary factor in the vertebrate host at the bite site and systemically during and after feeding by hematophagous (e.g., mosquitoes, ticks) and ectoparasitic (e.g., mites, chiggers, bed bugs) arthropods that influence pathogen transmission and pathogenesis, impact induction or inhibition of protective immune responses, or cause allergic responses. Another goal of this NOSI is to foster new and/or strengthen existing collaborations between vector biologists and immunologists.

This notice applies to due dates on or after October 5, 2024 and subsequent receipt dates through July 16, 2027.

NOT-AI-24-048

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Eligibility Requirements

This notice applies to due dates on or after October 5, 2024 and subsequent receipt dates through July 16, 2027.

Submit applications for this initiative using one of the following notice of funding opportunity announcements (NOFOs) or any reissues of these announcements through the expiration date of this notice.

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type:

Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA

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