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Notice of Special Interest (NOSI): Fundamental Science Research on Complementary and Integrative Health Approaches, Including Natural Products or Mind and Body Interventions

National Institutes of Health

The purpose of this Notice of Special Interest (NOSI) is to describe National Center of Complementary and Integrative Health (NCCIH) priorities in innovative basic and mechanistic research or technology/method development research relevant to complementary and integrative health approaches and their impact on health outcomes, resilience, and well-being.

Complementary health approaches include a broad range of practices and interventions that are not typically part of conventional medical care. Complementary approaches can be classified by their primary therapeutic input, which may be dietary (e.g., special diets, dietary supplements, herbs, prebiotics, and microbial-based therapies including probiotics), psychological (e.g., meditation, hypnosis, virtual reality, music-based interventions, relaxation therapies), physical (e.g., acupuncture, massage, chiropractic manipulation, light, devices related to these approaches), or a combination of psychological and physical (e.g., yoga, tai chi, dance therapies, some forms of art therapies). The dietary approaches include what have been previously categorized as natural products, whereas psychological and/or physical approaches encompass what have been commonly referred to as mind and body interventions. Integrative health brings conventional and complementary approaches together in a coordinated way. Integrative health also emphasizes multimodal interventions that aim to improve health in multiple interconnected domains, social, psychological, and physical, including multiple organs and systems.

This notice applies to due dates on or after October 7, 2024 and subsequent receipt dates through October 18, 2027.

NOT-AT-24-041