The purpose of this Notice is to encourage the submission of research project applications that enhance our understanding of the nature, extent, distribution, etiology, comorbidities, and consequences of drug use, misuse, and addiction across individuals, families, communities, and diverse population groups. Of interest are applications that address multiple levels of risk, resilience, and causation across scientific disciplines, and that apply novel methods to advance knowledge of the interplay among genetic, environmental, neurobiological, and developmental factors and associated health and disease outcomes. Priority will be given to research with a well described path towards translation and/or public health impact. In addition to novel data collection, approaches are encouraged that build on the research investments of NIH and sister HHS agencies to harness existing data on the epidemiology and etiology of drug misuse to improve public health prevention and treatment programs. The research areas noted below should be considered in the context of topics such as health disparities or inequities, familial/genetic liability, and physical, psychiatric, and polysubstance comorbidities and interactions.
NIDA seeks applications that allow for the advancement and translation of science, and that will inform our understanding of drug use and misuse epidemiology and etiology in a creative and cost-efficient manner. Of particular interest are studies that efficiently combine the advantages of epidemiological samples with behavioral, biological, neuroscience, and genetic measures, and that address differences in gender, race, ethnicity, socioeconomic status, and other health disparities or inequities, as well as projects that have the ability to identify and rapidly disseminate information about emerging drug trends. Supported research will have substantial public health impact and will inform basic, clinical, prevention, and services research to reduce the burden of drug use, misuse, and addiction on the nation's health.
This notice applies to due dates on or after June 5 2022 and subsequent receipt dates through September 8, 2025 .
NOT-DA-22-004
This notice applies to due dates on or after June 5 2022 and subsequent receipt dates through September 8, 2025 .
Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) or any reissues of these announcement through the expiration date of this notice
Sponsor Institute/Organizations: National Institutes of Health
Sponsor Type:
Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA
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Sep 08, 2025
Sep 08, 2025
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Affiliation: National Institutes of Health
Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA
Website URL: https://grants.nih.gov/grants/guide/notice-files/NOT-AA-24-007.html
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