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Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed)

National Institutes of Health

The purpose of this Notice of Special Interest (NOSI) is to stimulate novel epidemiological research to address key knowledge gaps within and between subpopulations of Asian Americans, Native Hawaiians, and Pacific Islanders. These populations are frequently aggregated in research, potentially masking important social and health differences. Given clear heterogeneity in ancestry, culture, immigration patterns among Asian Americans, socioeconomic position, and acculturation into American life, a critical need exists for epidemiological research to enhance our understanding of the interplay of environmental exposures, lifestyle, behavioral, genomics, social, neighborhood, and biological factors that impact the health of Asian American, Native Hawaiian, and Pacific Islander subpopulations.

The objective of this notice is to encourage fundamental epidemiological research geared toward understanding the inter-relationships of biological, lifestyle/behavioral, environmental, and sociocultural factors and how these factors may impact health disparities and outcomes in Asian American, Native Hawaiian, and Pacific Islander subpopulations. Epidemiological inference is enhanced with variation in study designs; therefore, investigators may leverage a range of design methods in response to this NOSI, including electronic health record databases, registries, cohort studies, and cross-sectional surveys. Applications may propose leveraging existing studies or data, or may propose new data collection.

To be considered responsive to this NOSI, applicants must propose to study at least one specific subpopulation of Asian Americans, Native Hawaiians, and Pacific Islanders. Applicants may propose to also include a non-Asian American, Native Hawaiian, or Pacific Islander population group as a comparator or proposed innovative analytical methods for within group comparisons as appropriate.

NOT-HL-23-001

Expiration Date: November 19, 2024