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Notice of Special Interest (NOSI): Behavioral and Social Science Priority Areas in Dementia Care Partner/Caregiver Research

National Institutes of Health

This Notice of Special Interest (NOSI) highlights priority areas of dementia care partner/caregiver research other than intervention development. Applications focused on care of persons living with dementia and the systems that provide care may cite NOT-AG-21-046 . Applications focused on the paid dementia care workforce may cite NOT-AG-21-049 . PLEASE NOTE: Applications proposing clinical trials will not be considered a high priority for this NOSI. Studies that focus on AD/ADRD behavioral intervention research are encouraged to explore whether PAR-21-307 , Dementia Care and Caregiver Support intervention Research (R01 – Clinical Trial Required) or PAR-21-308 , Pragmatic Trials for Dementia Care and Caregiver Support (R61/R33 – Clinical Trial Required) would be more appropriate.

This NOSI solicits high-priority Alzheimer's disease (AD) and AD-related dementias (ADRD) care partner/caregiver research areas as set forth by the National Institute on Aging’s Division of Behavioral and Social Research . Priority areas are guided by the AD/ADRD research implementation milestones and are based on expert discussions from the NIH 2020 Dementia Care Summit and recommendations from the NASEM Decadal Survey of Behavioral and Social Science Research on AD/ADRD .

Alzheimer’s disease directly affects more than 6 million Americans, most of them age 65 and older. The number of persons living with AD/ADRD is expected to increase significantly, given projected growth in the aging population, unless this disease can be effectively treated or prevented. The extensive care needs of individuals with AD/ADRD are highly variable and care typically involves great demands on spouses, family members (of origin or choice), and other care partners/caregivers. Care partners/caregivers may experience adverse health consequences (e.g., disrupted sleep, anxiety, depression, and compromised immune function) and economic hardship as a result of lost work and care expenditures. The challenges of caregiving may lead to institutional (e.g., nursing home) placement for persons with AD/ADRD instead of community-based and in-home care. Families that either partially or fully rely on unpaid support for care face significant out-of-pocket expenses. Access to high quality paid services and support, the level of care partner/caregiver engagement, and the quality of interactions with health care service providers can affect the health and well-being of both the care partner(s)/caregiver(s) and the person living with AD/ADRD.

This NOSI encourages behavioral and social research on care partners/caregivers for individuals with AD/ADRD. Care and care partner/caregiver support research can include multiple settings such as the home, community, or any formal care or clinical setting and address the individual, family, dyad, group, community, or health systems level. Applicants should specify the disease stage(s) and the population and setting/context under investigation.

This notice applies to due dates on or after March 11, 2022 and subsequent receipt dates through November 13, 2024.

Application Due Date(s): March 11, 2022; July 8, 2022; Nov 14, 2022; March 10, 2023; July 10, 2023; Nov 13, 2023; March 11, 2024; July 9, 2024; Nov 12, 2024

NOT-AG-21-047

Specialties

Behavioural Sciences

Psychology

Neurosciences

Public Health

Eligibility Requirements

All are eligible.

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type:

Address: National Institutes of Health; 31 Center Drive; MSC 2220; Bethesda; MD 20892-2220; USA

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