The Cancer Screening and Early Detection RFA solicits applications for eligible projects up to 5 years in duration that will deliver evidence-based clinical services in cancer detection and screening for breast, cervical, colorectal, liver, and lung cancers according to established and current national guidelines and criteria. Projects with a focus on guidelines-informed screening and early detection of subsequent treatment-related cancers in survivor populations are eligible. Nonmetropolitan (rural) and/or medically underserved populations must be included in the defined service area.
The following are required components of the project:
• Geographic Area to be Served: Clinical service delivery to nonmetropolitan/medically underserved area (MUA) counties must be included in the defined service area. Rural and MUA counties may be identified via web-based tools from the US Department of Health and Human Services. Service to urban/nonmedically underserved counties is allowable if the project proposes to also serve nonmetropolitan/medically underserved counties.
• Comprehensive Projects: Comprehensive projects include a continuum of services and systems and policy changes and comprise all the following: Public and professional education and training, outreach, delivery of screening and diagnostic services, follow-up navigation into treatment services for those diagnosed with cancer and precancer, data collection and tracking, and systems improvement. Evidence Based: CPRIT’s secondary prevention grants are intended to fund effective and efficient systems of delivery of early detection services based on the existing body of knowledge about and evidence for screening for both primary and secondary cancers in ways that far exceed current performance in a given service area. The provision of clinical services, including rescreening at the appropriate interval, must comply with established and current national guidelines (eg, US Preventive Services Task Force [USPSTF], American Cancer Society [ACS], Children’s Oncology Group [COG] LongTerm Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers). The National Comprehensive Cancer Network, ACS, and COG have developed consensus-based comprehensive survivorship care guidelines to provide direction on managing the potential physical and psychosocial long-term impact of cancer/associated treatment and subsequent surveillance for recurrence and screening for second primary cancers for projects focusing on survivor care. If evidence-based strategies have not been implemented or tested for the specific population or service setting proposed, provide evidence that the proposed service is appropriate for the population and has a high likelihood of success.
• Clinical Service and Community Partner Networks: Applicants are strongly encouraged to coordinate and describe a collaboration of clinical service providers and community partners that can deliver outreach, education, clinical, and navigation services to the most counties and the most people possible in a selected service region. Applicants should consider providing financial assistance to service providers for navigation services. Partnerships with other organizations that can support and leverage resources (eg, community-based organizations, local and voluntary agencies, nonprofit agencies,groups that represent priority populations) are encouraged. Letters of commitment or memoranda of understanding (MOUs) describing their specific role in the partnership will strengthen the application.
Funding maximums are for the entire grant period and are inclusive of both direct and indirect costs.
• The applicant must be a Texas-based entity, such as a community-based organization, health institution, government organization, public or private company, college or university, or academic health institution.
• The applicant is eligible solely for the grant mechanism specified by the RFA under which the grant application was submitted.
• The designated PD will be responsible for the overall performance of the funded project. The PD must have relevant education and management experience and must reside in Texas during the project performance time.
• The evaluation of the project must be headed by a professional who has demonstrated expertise in the field and who resides in Texas during the time that the project is conducted.
• The applicant may submit more than 1 application, but each application must be for distinctly different services without overlap in the services provided. Applicants who do not meet this criterion will have all applications administratively withdrawn without peer review.
• If an organization has a current CPRIT grant that is the same or similar to the prevention intervention being proposed, the applicant must explain how the projects are nonduplicative or complementary. Duplicative applications will be administratively withdrawn.
• If the applicant or a partner is an existing Department of State Health Services contractor, CPRIT funds may not be used as a match, and the application must explain how this grant complements or leverages existing state and federal funds.
• Collaborations are permitted and encouraged, and collaborators may or may not reside in Texas. However, collaborators who do not reside in Texas are not eligible to receive CPRIT funds. Subcontracting and collaborating organizations may include public, notfor-profit, and for-profit entities. Such entities may be located outside of the State of Texas, but non-Texas-based organizations are not eligible to receive CPRIT funds.
• An applicant is not eligible to receive a CPRIT grant award if the applicant PD, any senior member or key personnel listed on the grant application, or any officer or director of the grant applicant’s organization or institution is related to a CPRIT Oversight Committee member.
• An applicant organization is eligible to receive a grant award only if the applicant certifies that the applicant organization, including the PD, any senior member or key personnel listed on the grant application, or any officer or director of the grant applicant’s organization (or any person related to 1 or more of these individuals within the second degree of consanguinity or affinity), has not made and will not make a contribution to CPRIT or to any foundation created to benefit CPRIT.
• The applicant must report whether the applicant organization, the PD, or other individuals who contribute to the execution of the proposed project in a substantive, measurable way (whether slated to receive salary or compensation under the grant award or not), are currently ineligible to receive federal grant funds because of scientific misconduct or fraud or have had a grant terminated for cause within 5 years prior to the submission date of the grant application.
• CPRIT grants will be awarded by contract to successful applicants. CPRIT grants are funded on a reimbursement-only basis. Certain contractual requirements are mandated by Texas law or by administrative rules. Although applicants need not demonstrate the ability to comply with these contractual requirements at the time the application is submitted, applicants should make themselves aware of these standards before submitting a grant application. Significant issues addressed by the CPRIT contract are listed in section 6. All statutory provisions and relevant administrative rules can be found on the CPRIT website.
Eligible Countries:
Sponsor Institute/Organizations: Cancer Prevention and Research Institute of Texas
Sponsor Type: Corporate/Non-Profit
Address: 1701 North Congress Avenue, Suite 6-127 Austin, TX 78701
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Jun 11, 2025
Jun 11, 2025
$2,500,000
Affiliation: Cancer Prevention and Research Institute of Texas
Address: 1701 North Congress Avenue, Suite 6-127 Austin, TX 78701
Website URL: https://cprit.texas.gov/media/3703/rfa-p-261-csd-final_revised.pdf
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