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Funding Opportunity




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Alzheimer’s Disease Research-Standard Awards

BrightFocus Foundation

This research grant program is restricted to new and early investigators who have obtained their MD, PhD, or equivalent degree and/or completed formal medical training/residency within the past 12 years at the time of application. The applicant must serve as the principal investigator on the project, have institutional permission to manage the award, and the key personnel associated with the proposal.

  • Award Amount: $300,000
  • Duration: 3 years

AI Based Application Success Predictor

1. 🎯 Direct Relevance to Target Diseases

BrightFocus funds projects focused on:

Alzheimer’s disease and related dementias

Age-related macular degeneration (AMD)

Glaucoma and optic nerve degeneration

Predictor: The project must directly contribute to understanding, preventing, or treating these conditions.

2. 👩‍🔬 Support for Early-Career Investigators

Many programs are aimed at postdocs, junior faculty, and new investigators

Strong mentorship and career development plans improve success chances

Predictor: Applicants are early-career researchers with strong mentors and institutional support.

3. 🧪 Novel, High-Risk/High-Reward Research

BrightFocus values innovative, cutting-edge approaches

Projects should generate preliminary data leading to NIH or larger foundation funding

Predictor: The proposal is innovative but feasible within a 1–2 year timeframe.

4. 📚 Alignment with BrightFocus Mission

Proposals must aim to understand mechanisms, identify biomarkers, or develop treatments

Translational potential is highly valued

Predictor: The application clearly connects to improving patient outcomes.

5. 📈 Potential for Impact and Career Advancement

Funded projects often lead to:

Publications in high-impact journals

Follow-on NIH or international grants

Predictor: The applicant shows strong potential for significant contributions to the field.

🧾 BrightFocus Grant Programs

ProgramAmountAudiencePurpose
Alzheimer’s Disease Research Grants$100k–$300kPostdocs, junior facultyBasic or translational AD research
National Glaucoma Research Grants$100k–$200kResearchersMechanisms, biomarkers, treatments for glaucoma
Macular Degeneration Research Grants$100k–$300kInvestigatorsResearch to prevent or treat AMD

 

📌 Tips for Strong Applications

✅ Provide clear hypotheses and innovative methods
✅ Include letters of mentorship and institutional support (if early-career)
✅ Show how results will lead to future NIH or foundation grants
✅ Emphasize translational relevance to patient care

Specific eligibility criteria include: 

• Candidates must hold an MD, PhD, DVM, DO, OD or equivalent degree and be within 12 years of conferral 

• Applicant must serve as the Principal Investigator on the project and have dedicated laboratory space. The applicant should use the indicated space on the application forms to clarify any position that is not immediately recognizable as an independent research position 

• While some of the grant can be used to support salary for the PI, the percent requested should be limited to the lesser of 35% of the yearly grant request, or 35% of the individual’s salary. Co-Principal Investigator (Co-PI) salaries are capped at the lesser of 25% of the yearly grant request, or 25% of the individual’s salary. 

• Applicants may currently be working in a non-profit, governmental, academic research institution, or at a for-profit including start-up and biotech institution

Sponsor Institute/Organizations: BrightFocus Foundation

Sponsor Type: Corporate/Non-Profit

Address: 22512 Gateway Center Drive Clarksburg, MD 20871

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Grant

Final Deadline:

Sep 29, 2025

Funding Amount:

$300,000

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