Lung cancer continues to be the number one cause of cancer deaths worldwide, accounting for an estimated 127,070 deaths annually in the United States alone1 . Despite being the most common cancer killer for both men and women, lung cancer research remains critically underfunded. To help close this gap and improve outcomes, the goal of the 2024 LCRF Leading Edge Research Grant Program is to fund innovative projects across the full spectrum of basic, translational, clinical, epidemiological, health services, early detection, disparities, and social determinants of health research. 2024 LCRF Leading Edge Research Grant Program will provide $150,000 over a period of two years for projects including but not limited to the following topics:
• Lung cancer biology
• Risk reduction and screening for early detection
• Identification of new biomarkers
• Development of more effective and less toxic therapies including but not limited to targeted and immune-therapies
• Genetic and gene-environment interactions
• Interactions and contributions of multiple factors (e.g. smoking, genetics, environment, societal factors) to disparities in lung cancer outcomes
• Mechanisms of sensitivity and resistance to lung cancer therapies
• Bioengineering approaches to understanding and/or treating lung cancer (i.e., theranostics, biomaterials, nanotechnology, controlled-drug release, and gene-therapy)
• Supportive measures for people with lung cancer and their families
• Identification of metabolic vulnerabilities in lung cancer
Budget Requirements The maximum award amount is $150,000 for a period of two years (disbursed at $75,000 per year). Additional budget requirements and considerations include the following:
• Funding from this award may not be used to support institutional indirect / facilities and administrative costs.
• The LCRF grant must be the primary source of support for the project. Additional secondary funding (e.g. for core services support) is permitted.
• There is no limit on the amount of salary support that may be requested. However, appropriate justification for all budget items is required. Any salary requests in excess of 20% of the total budget must be explicitly justified.
• Any equipment costs must be limited and directly applicable to the research project (i.e. large, general equipment costs are not permitted).
• Direct patient care costs reimbursable by other sources may not be included.
• Travel and publication costs are permitted.
Investigators must be affiliated with a non-profit academic or research institution and must be post-doctoral researchers, clinical fellows, or early-career and mid-career investigators with less than ten years’ experience since their initial faculty appointment. Applicants from US-based and international institutions are eligible to apply and may hold any residency/citizenship status. Applicants are prohibited from applying if they have received funding from the LCRF within the last 4 years. Senior investigators with more than ten years’ experience since faculty appointment are generally not eligible for funding and are encouraged to mentor a junior team member through the application process. However, exceptions will be made for investigators with more than ten years’ experience in other disease areas or topicsIneligible investigators with these or other special circumstances may request review by contacting the LCRF grants office (see Inquiries section below) before submitting an application.
Sponsor Institute/Organizations: Lung Cancer Research Foundation
Sponsor Type:
Address: 501 7th Avenue, Suite 401 New York, NY 10018 United States
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Mar 03, 2025
Jun 02, 2025
$150,000
Affiliation: Lung Cancer Research Foundation
Address: 501 7th Avenue, Suite 401 New York, NY 10018 United States
Website URL: https://www.lungcancerresearchfoundation.org/wp-content/uploads/2024-LCRF-Leading-Edge-Proposal-Final.pdf
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